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"...this book serves as a useful manifesto of the approach to bioinformatics taken by NCBI. In particular, the discussion of the NCBI Data Model, the information retrieval philosophy, GenBank, the structure databases and creation useful glimpse at the underlying logic and philosophy behind the services provided by the center....this is a worthwhile addition to the library as a reference guide for biologists using computational resources, and desiring an introduction to the use of some important tools....bioinformatics professionals should also have this book because of its excellent treatment of some areas."-FEBS Letters