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Inhaltsangabe
SECTION I Carbohydrate-Protein Interactions: Plant and Animal Lectins.- I-1 The Structural Basis for Carbohydrate Recognition by Lectins.- I-2 Lectin Cross-linking Interactions with Multivalent Carbohydrates.- I-3 Classification of Plant Lectins in Families of Structurally and Evolutionary Related Proteins.- I-4 Expression of Binding Properties of Gal/Ga1NAc Reactive Lectins by Mammalian Glycotopes.- I-5 'Glyco-Epitope' Assignments for the Selectins: Advances Enabled by the Neoglycolipid Technology in Conjunction with Synthetic Carbohydrate Chemistry.- I-6 Animal Lectins: From Initial Description to Elaborated Structural and Functional Classification.- I-7 Galectins and Other Endogenous Carbohydrate-Binding Proteins of Animal Bladder.- I-8 Binding Properties and Applications of Aplysia Gonad Lectin.- I-9 Lectin and Anti-carbohydrate Antibody Assays Using Chemically Modified Ligands.- SECTION II Structure and Antigenicity of Glycoconjugates.- II-1 Intramolecular Carbohydrate-Protein Interaction.- II-2 Red Blood Cell Antigens Responsible for Inherited Types of Polyagglutination.- II-3 Antigenic Properties of Human Glycophorins-An Update.- II-4 KDN-Containing Glycoprotein from Loach Skin Mucus.- II-5 Glycoconjugates from Parasitic Helminths: Structure Diversity and Immunobiological Implications.- II-6 Glycosyl Phosphatidylinositol-Linked Glycoconjugates: Structure, Biosynthesis, and Function.- II-7 Enzymatic and Chemical Approaches for the Synthesis of Sialyl Glycoconjugates.- SECTION III Glycotopes Expression, Metabolism, and Functions.- III-1 The Genetic Regulation of Fucosylated and Sialylated Antigens on Developing Myeloid Cells.- III-2 Transcriptional Regulation of Expression of Carbohydrate Ligands for Cell Adhesion Molecules in the Selectin Family.- III-3Biosynthesis and Function of ?1,6 Branched Mucin-Type Glycans.- III-4 Differentiation-Associated Expression of ß-N-acetylgalactosaminylated N-linked Oligosaccharides in Mammary Epithelial Cells.- III-5 Metabolism and Role of O-Acetylated Sialic Acids.- III-6 Contradictory Functions of the Sulfatide in the Blood Coagulation System.- III-7 Interaction of GM2 Activator Protein with Glycosphingolipids.- SECTION IV Complex Carbohydrates in Development and Treatment of Cancer.- IV-1 Tumor-Associated Carbohydrate Antigens Defining Tumor Malignancy: Basis for Development of Anti-cancer Vaccines.- IV-2 Carbohydrate-Mediated Adhesion of Human Colon Carcinoma Cells to Human Liver Sections.- IV-3 O-Linked N-Acetylglucosamine and Cancer: Messages from the Glycosylation of c-Myc.- IV-4 Analysis of a Murine Anti-Ganglioside GD2 Monoclonal Antibody Expressing Both IgG2a and IgG3 Isotypes: Monoclonality, Apoptosis Triggering, and Activation of Cellular Cytotoxicity on Human Melanoma Cells.- SECTION V Complex Carbohydrates in Microbial and Viral Infections and Vaccine Design.- V-1 Pathogen-Host Protein-Carbohydrate Interactions as the Basis of Important Infections.- V-2 Host Mediated Variation and Receptor Binding Specificity of Influenza Viruses.- V-3 Bacterial Polysaccharides as Vaccines - Immunity and Chemical Characterization.- V-4 The Conformational Epitope of Type III Group B Streptococcus Capsular Polysaccharide.- V-5 T-independent IgA Responses to Microbial Polysaccharides.- V-6 Protective Immunity and Gene Expression Related to Pneumococcal Glycoconjugates.- V-7 Structure and Functional Genomics of Lipopolysaccharide Expression in Haemophilus influenzae.- V-8 Molecular Mimicry of Host Structures by Lipooligosaccharides of Neisseria meningitidis: Characterization ofSialylated and Nonsialylated Lacto-N-Neotetraose (Gal?1-4G1cNAc?1-3Gal?1-4Glc) Structures in Lipooligosaccharides using Monoclonal Antibodies and Specific Lectins.- V-9 NMR and Molecular Modeling of Complex Carbohydrates and Carbohydrate-Protein Interactions: Applications to Anti-bacteria Vaccines.- Append.- A-I A Guide to the Carbohydrate Specificities of Applied Lectins-2 (Updated in 2000).- A-II A Guide to Monoclonal Antibodies Directed to Glycotopes.
SECTION I Carbohydrate-Protein Interactions: Plant and Animal Lectins.- I-1 The Structural Basis for Carbohydrate Recognition by Lectins.- I-2 Lectin Cross-linking Interactions with Multivalent Carbohydrates.- I-3 Classification of Plant Lectins in Families of Structurally and Evolutionary Related Proteins.- I-4 Expression of Binding Properties of Gal/Ga1NAc Reactive Lectins by Mammalian Glycotopes.- I-5 'Glyco-Epitope' Assignments for the Selectins: Advances Enabled by the Neoglycolipid Technology in Conjunction with Synthetic Carbohydrate Chemistry.- I-6 Animal Lectins: From Initial Description to Elaborated Structural and Functional Classification.- I-7 Galectins and Other Endogenous Carbohydrate-Binding Proteins of Animal Bladder.- I-8 Binding Properties and Applications of Aplysia Gonad Lectin.- I-9 Lectin and Anti-carbohydrate Antibody Assays Using Chemically Modified Ligands.- SECTION II Structure and Antigenicity of Glycoconjugates.- II-1 Intramolecular Carbohydrate-Protein Interaction.- II-2 Red Blood Cell Antigens Responsible for Inherited Types of Polyagglutination.- II-3 Antigenic Properties of Human Glycophorins-An Update.- II-4 KDN-Containing Glycoprotein from Loach Skin Mucus.- II-5 Glycoconjugates from Parasitic Helminths: Structure Diversity and Immunobiological Implications.- II-6 Glycosyl Phosphatidylinositol-Linked Glycoconjugates: Structure, Biosynthesis, and Function.- II-7 Enzymatic and Chemical Approaches for the Synthesis of Sialyl Glycoconjugates.- SECTION III Glycotopes Expression, Metabolism, and Functions.- III-1 The Genetic Regulation of Fucosylated and Sialylated Antigens on Developing Myeloid Cells.- III-2 Transcriptional Regulation of Expression of Carbohydrate Ligands for Cell Adhesion Molecules in the Selectin Family.- III-3Biosynthesis and Function of ?1,6 Branched Mucin-Type Glycans.- III-4 Differentiation-Associated Expression of ß-N-acetylgalactosaminylated N-linked Oligosaccharides in Mammary Epithelial Cells.- III-5 Metabolism and Role of O-Acetylated Sialic Acids.- III-6 Contradictory Functions of the Sulfatide in the Blood Coagulation System.- III-7 Interaction of GM2 Activator Protein with Glycosphingolipids.- SECTION IV Complex Carbohydrates in Development and Treatment of Cancer.- IV-1 Tumor-Associated Carbohydrate Antigens Defining Tumor Malignancy: Basis for Development of Anti-cancer Vaccines.- IV-2 Carbohydrate-Mediated Adhesion of Human Colon Carcinoma Cells to Human Liver Sections.- IV-3 O-Linked N-Acetylglucosamine and Cancer: Messages from the Glycosylation of c-Myc.- IV-4 Analysis of a Murine Anti-Ganglioside GD2 Monoclonal Antibody Expressing Both IgG2a and IgG3 Isotypes: Monoclonality, Apoptosis Triggering, and Activation of Cellular Cytotoxicity on Human Melanoma Cells.- SECTION V Complex Carbohydrates in Microbial and Viral Infections and Vaccine Design.- V-1 Pathogen-Host Protein-Carbohydrate Interactions as the Basis of Important Infections.- V-2 Host Mediated Variation and Receptor Binding Specificity of Influenza Viruses.- V-3 Bacterial Polysaccharides as Vaccines - Immunity and Chemical Characterization.- V-4 The Conformational Epitope of Type III Group B Streptococcus Capsular Polysaccharide.- V-5 T-independent IgA Responses to Microbial Polysaccharides.- V-6 Protective Immunity and Gene Expression Related to Pneumococcal Glycoconjugates.- V-7 Structure and Functional Genomics of Lipopolysaccharide Expression in Haemophilus influenzae.- V-8 Molecular Mimicry of Host Structures by Lipooligosaccharides of Neisseria meningitidis: Characterization ofSialylated and Nonsialylated Lacto-N-Neotetraose (Gal?1-4G1cNAc?1-3Gal?1-4Glc) Structures in Lipooligosaccharides using Monoclonal Antibodies and Specific Lectins.- V-9 NMR and Molecular Modeling of Complex Carbohydrates and Carbohydrate-Protein Interactions: Applications to Anti-bacteria Vaccines.- Append.- A-I A Guide to the Carbohydrate Specificities of Applied Lectins-2 (Updated in 2000).- A-II A Guide to Monoclonal Antibodies Directed to Glycotopes.
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