The Postmortem Brain in Psychiatric Research (eBook, PDF)

Redaktion: Agam, Galila; Belmaker, Robert Haim; Everall, Ian P.

• Format: PDF

Produktbeschreibung

Because of the dearth of experimental animal models of psychiatric disorders, the study of the effect of the disease state is only possible in tissue derived from patients vs. controls, especially in the target tissue of disease-related changes in the brain. The human postmortem brain offers the most appropriate experimental paradigm towards understanding the etiology of psychiatric disorders. The availability of post-mortem human samples from psychiatric patients and comparison groups in recent years has contributed prominently to the accumulating body of information leading to a better understanding of these disorders. This is the first book to summarize this research approach and the meaningful data which has recently been acquired.

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Produktdetails

• Verlag: Springer US
• Seitenzahl: 404
• Erscheinungstermin: 9. März 2013
• Englisch
• ISBN-13: 9781475736311
• Artikelnr.: 44042799

Inhaltsangabe

Contributors. Acknowledgements. Introduction; E.F. Torrey, M.B. Knable. Methodology and General Findings. 1. Psychiatric Brain Banks: Situation in Europe and Asia; I. Matsumoto, S.I. Niwa, R. Ravid. 2. Methodological and Stereological Considerations in Postmortem Psychiatric Brain Research; I.P. Everall, P.J. Harrison. 3. Imaging vs. Postmortem Receptor Studies: What You See is What You Get? L. Pilowsky. 4. Glial Pathology and Major Psychiatric Disorders; D.R. Cotter, C.M. Pariante, G. Rajkowska. 5. Indications of Abnormal Connectivity in Neuropsychiatric Disorders and Postmortem Studies; W.G. Honer. 6. Studies in the Human Frontal Cortex: Evidence for Changes in Neurochemical Markers in Schizophrenia and Bipolar Disorder; B. Dean. 7. Summary of Prefrontal Molecular Abnormalities in the Stanley Foundation Neuropathology Consortium; M.B. Knable, B.M. Barci, M.J. Webster, E.F. Torrey. Schizophrenia. 8. Macroanatomical Findings in Postmortem Brain Tissue from Schizophrenic Patients;