The story opens with Ishmael, his family, Ellen and Abiram slowly making their way across the virgin prairies of the Midwest looking for a homestead, just two years after the Louisiana Purchase, and during the time of the Lewis and Clark Expedition. They meet the trapper (Natty Bumppo), who has left his home in New York state to find a place where he cannot hear the sound of people cutting down the forests. In the years between his other adventures and this novel, he tells us only that he has walked all the way to the Pacific Ocean and seen all the land between the coasts (a heroic feat, considering Lewis and Clark hadn’t yet completed the same trek). That night, a band of Teton warriors steal all of Ishmael’s animals, stranding the immigrants. The doctor returns the next morning along with his donkey. The trapper helps the family relocate their wagons, including one with mysterious contents, to a nearby butte where they will be safer when the Tetons return. Middleton joins the group when he stumbles upon the trapper and Paul. Before they return to the butte, Ishmael and his family go looking for his eldest son, Asa, whom they find murdered...