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During the mid- to late-twentieth century, study of the physiology of the developing fetus and newborn infant evolved rapidly to become a major discipline in the biomedical sciences. Initially of interest from a standpoint of function of the placenta and oxygenation of the fetus, the field advanced to explore both normal functional mechanisms as well as pathophysiologic aspects of their regulation. Examples include studying the role and regulation of circulatory vascular anatomic shunts in oxygenation, cardiac function, certain aspects of asphyxia in the fetus and newborn infant, the role of…mehr
During the mid- to late-twentieth century, study of the physiology of the developing fetus and newborn infant evolved rapidly to become a major discipline in the biomedical sciences. Initially of interest from a standpoint of function of the placenta and oxygenation of the fetus, the field advanced to explore both normal functional mechanisms as well as pathophysiologic aspects of their regulation. Examples include studying the role and regulation of circulatory vascular anatomic shunts in oxygenation, cardiac function, certain aspects of asphyxia in the fetus and newborn infant, the role of fetal “breathing” movements, cyclic electroencephalographic activity, and analysis of electronic monitoring of fetal heart rate variability and its significance.
Included in this book are reminisces of several dozen individuals who played a vital role in these developments. Overall, this survey considers a number of aspects of the development of the science of fetal and neonatal physiology, and its role in the greatly improved care of pregnant women and their newborn infants.
This book is published on behalf of the American Physiological Society by Springer. Access to APS books published with Springer is free to APS members.
Lawrence P. Longo (1926-2016) Formerly at Loma Linda University School of Medicine, Center for Perinatal Biology, Loma Linda, CA, USA
Inhaltsangabe
Introduction.- A Scientific Genealogy: The Development of Fetal-Neonatal Research.- Oxford and the Development of Physiology, with Notes on the Nuffield Institute.- Geoffrey S. Dawes: A Life in Science.- Dawes and Fetal Asphyxia: The Primate Colony in Puerto Rico.- Dawes, the Pulmonary Vasculature and his Foetal and Neonatal Physiology.- Embryology and Early Developmental Physiology.- Some Aspects of the Physiology of the Placenta.- Governmental Support of Research in Fetal and Newborn Physiology.- Fetal-Neonatal Growth and Metabolism.- Epigenetics and the Fetal Origins of Adult Heath and Disease.- Related Developments in Fetal and Neonatal Endocrinology.- Further Developments in Fetal and Neonatal Physiology.- Some Clinical Aspects of Developmental Physiology.- Bioethical Issues in Research on the Fetus and Newborn Infant.- Textbooks, Monographs and other Volumes on Fetal and Newborn Physiology.- Dawes and Fetal “Breathing” in the 1970s, and Fetal Heart Rate Analysis in the 1980s and early 1990s.- Dawes’ Contributions to Symposia and a Summing Up.- Dawes as a Mentor: Reminisces of Former Graduate Students, Postdoctoral Fellows, and Associates.- Early Years of the Society for Gynecologic Investigation, the Fetal and Neonatal.- Epilogue.- Index.
Introduction.- A Scientific Genealogy: Early Development of Fetal-Neonatal Research.- Oxford and the Development of Physiology, with Notes on the Nuffield Institute for Medical Research.- Geoffrey S. Dawes: A Life in Science.- Fetal Asphyxia and The Primate Colony in Puerto Rico.- The Pulmonary Vasculature and Dawes' Foetal and Neonatal Physiology.- Embryology and Early Developmental Physiology.- Some Aspects of the Physiology of the Placenta.- Some Aspects of Endocrinology of the Placenta.- Maternal Physiology of Pregnancy.- Maternal Complications of Pregnancy that Affect Fetal/Newborn Development.- Fetal Growth and its Restriction.- Fetal-Neonatal Growth and Metabolism.- Fetal Growth Restriction at High Altitude: Clinical Observations.- Fetal Growth Restriction at High Altitude: Basic Cellular and Subcellular Physiologic Considerations.- Epigenetics and the Fetal Origins of Adult Health and Disease.- Some Aspects of the Developing Brain and Nervous S
ystem.- Related Developments in Fetal and Neonatal Endocrinology.- Further Developments in Fetal and Neonatal Physiology.- Additional Clinical Aspects of Developmental Physiology and Clinical Care.- Governmental Support of Research in Fetal and Newborn Physiology.- Bioethical Issues in Research on the Fetus and Newborn Infant.- Textbooks, Monographs and other Volumes on Fetal and Newborn Physiology.- Fetal "Breathing" in the 1970s, and Fetal Heart Rate Analysis in the 1980s and Early 1990s.- Dawes' Contributions to Symposiaand a Summing Up.- Dawes as a Mentor: Reminisces of Former Graduate Students, Postdoctoral Fe Early Years of The Society for Reproductive Investigation (formerly Society for Gynecologic Investigation), the Fetal and Neonatal Physiological Society, and Several Other Groups.- The Reproductive Scientist Development Program and Related Programs.- Epilogue.- Bibliography of Geoffrey S. Dawes.
Introduction.- A Scientific Genealogy: The Development of Fetal-Neonatal Research.- Oxford and the Development of Physiology, with Notes on the Nuffield Institute.- Geoffrey S. Dawes: A Life in Science.- Dawes and Fetal Asphyxia: The Primate Colony in Puerto Rico.- Dawes, the Pulmonary Vasculature and his Foetal and Neonatal Physiology.- Embryology and Early Developmental Physiology.- Some Aspects of the Physiology of the Placenta.- Governmental Support of Research in Fetal and Newborn Physiology.- Fetal-Neonatal Growth and Metabolism.- Epigenetics and the Fetal Origins of Adult Heath and Disease.- Related Developments in Fetal and Neonatal Endocrinology.- Further Developments in Fetal and Neonatal Physiology.- Some Clinical Aspects of Developmental Physiology.- Bioethical Issues in Research on the Fetus and Newborn Infant.- Textbooks, Monographs and other Volumes on Fetal and Newborn Physiology.- Dawes and Fetal “Breathing” in the 1970s, and Fetal Heart Rate Analysis in the 1980s and early 1990s.- Dawes’ Contributions to Symposia and a Summing Up.- Dawes as a Mentor: Reminisces of Former Graduate Students, Postdoctoral Fellows, and Associates.- Early Years of the Society for Gynecologic Investigation, the Fetal and Neonatal.- Epilogue.- Index.
Introduction.- A Scientific Genealogy: Early Development of Fetal-Neonatal Research.- Oxford and the Development of Physiology, with Notes on the Nuffield Institute for Medical Research.- Geoffrey S. Dawes: A Life in Science.- Fetal Asphyxia and The Primate Colony in Puerto Rico.- The Pulmonary Vasculature and Dawes' Foetal and Neonatal Physiology.- Embryology and Early Developmental Physiology.- Some Aspects of the Physiology of the Placenta.- Some Aspects of Endocrinology of the Placenta.- Maternal Physiology of Pregnancy.- Maternal Complications of Pregnancy that Affect Fetal/Newborn Development.- Fetal Growth and its Restriction.- Fetal-Neonatal Growth and Metabolism.- Fetal Growth Restriction at High Altitude: Clinical Observations.- Fetal Growth Restriction at High Altitude: Basic Cellular and Subcellular Physiologic Considerations.- Epigenetics and the Fetal Origins of Adult Health and Disease.- Some Aspects of the Developing Brain and Nervous S
ystem.- Related Developments in Fetal and Neonatal Endocrinology.- Further Developments in Fetal and Neonatal Physiology.- Additional Clinical Aspects of Developmental Physiology and Clinical Care.- Governmental Support of Research in Fetal and Newborn Physiology.- Bioethical Issues in Research on the Fetus and Newborn Infant.- Textbooks, Monographs and other Volumes on Fetal and Newborn Physiology.- Fetal "Breathing" in the 1970s, and Fetal Heart Rate Analysis in the 1980s and Early 1990s.- Dawes' Contributions to Symposiaand a Summing Up.- Dawes as a Mentor: Reminisces of Former Graduate Students, Postdoctoral Fe Early Years of The Society for Reproductive Investigation (formerly Society for Gynecologic Investigation), the Fetal and Neonatal Physiological Society, and Several Other Groups.- The Reproductive Scientist Development Program and Related Programs.- Epilogue.- Bibliography of Geoffrey S. Dawes.
Rezensionen
"This is the second edition of a historical book first published in 2013 to document the contributions of several key researchers and clinicians to the advancement of knowledge in the field of perinatal medicine. ... The purpose is to give clinicians, researchers, and historians a personal view of how much of the science in this field was developed ... . this book would be of interest to anyone curious about the research and development of this field." (Jay P. Goldsmith,Doody's Book Reviews, April, 2018)
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