The Role of Brain Dopamine (eBook, PDF)

Illustrator: Haley, Jack

• Format: PDF

Produktbeschreibung

As in other volumes in the series, this newest volume conveys up-to-date knowledge in a clear and straightforward manner. It begins with a survey of the neurobiological functions of the brain, with the emphasis on Parkinson's disease. This is followed by a presentation of the role of dopamine in the regulation of human anterior pituitary function. The final two chapters concentrate on the dopamine receptors: first, the binding sites are characterized and the biochemical and physiological consequences of dopamine-receptor stimulation are discussed and, finally, there is a report on the topology of a dopamine-receptor model that can account comprehensively for agonists and antagonists.

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Produktdetails

• Verlag: Springer Berlin Heidelberg
• Seitenzahl: 55
• Erscheinungstermin: 6. Dezember 2012
• Englisch
• ISBN-13: 9783642738975
• Artikelnr.: 53125961

Inhaltsangabe

The Role of Dopamine in the Control of Neurobiological Functions.- Parkinson's Disease.- Senile Dementia of the Alzheimer Type.- A DA Hypothesis of Schizophrenia.- DA in Affective Disorders.- References.- Clinical Aspects of Dopamine in the Regulation of Human Anterior Pituitary Function.- Regulation of Prolactin Secretion.- Clinical Features of Hyperprolactinaemia.- Diagnosis of Hyperprolactinaemia.- Natural History of Prolactinomas.- Therapy.- Macroprolactinomas.- Dopamine and LH Secretion.- Dopamine in Growth Hormone Secretion.- Dopamine Agonist Therapy for Acromegaly.- Dopamine and ACTH Secretion.- Conclusions.- References.- Dopamine Receptors in the Central Nervous System.- Receptors and Second Messengers.- Second Messengers and Dopamine Receptors.- Binding Sites for Dopamine Receptor Ligands.- Biochemical and Physiological Manifestations of Dopamine Receptor Stimulation.- Behavioural Manifestations of Dopamine Receptor Stimulation.- Conclusions.- References.- Topology of Dopamine Receptors.- Dopamine Agonists.- Dopamine Antagonists.- Unsolved Problems: D1/D2 Specificity and Partial Agonists.- Conclusion.- References.