The Role of Immune Mechanisms in Cardiovascular Disease (eBook, PDF)

Redaktion: Schultheiss, Heinz-Peter; Schwimmbeck, Peter

• Format: PDF

Produktbeschreibung

This book offers a unique description of different immunological aspects of myocardial disease. With contributions from numerous leading experts, the volume reflects state-of-the art knowledge in the field. The topics covered include classical aspects of inflammation in myocardial disease such as myocarditis and transplant rejection as well as arteriosclerosis. The latest therapeutic approaches to treatment are presented, making the book appeal to both scientists and clinical cardiologists.

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Produktdetails

• Verlag: Springer Berlin Heidelberg
• Seitenzahl: 319
• Erscheinungstermin: 6. Dezember 2012
• Englisch
• ISBN-13: 9783642604638
• Artikelnr.: 53384746

Inhaltsangabe

The Immunology of Myocarditis.- Mechanisms and Genetics of Autoimmunity.- Molecular Pathogenesis of Myocarditis and Cardiomyopathy: Analysis of Virus-Receptor Interactions and Tyrosine Phosphorylation Events.- Coxsackievirus Genetics and the Cardiovirulent Viral Phenotype.- Lessons from Animal Models of Viral Myocarditis.- The Role of Cytokines in the Pathogenesis of Myocarditis.- The Role of Heart Infiltrating Cells in Myocyte Injury.- The Significance of T Cell Responses in Human Myocarditis.- The Possible Pathogenic Role of Autoantibodies in Myocarditis and Dilated Cardiomyopathy.- The Adenine Nucleotide Translocator: A Major Autoantigen in Myocarditis and Dilated Cardiomyopathy.- Immunohistochemical Analysis of Inflammatory Heart Disease.- Immunological Mediators in Inflammation of the Heart.- Adhesion Molecule Induction and Expression in Neutrophil-Induced Myocardial Injury.- Molecular Mechanisms of Adhesion of Staphylococcus Aureus to Cardiac Surfaces and Vegetations.- Endotoxins as Potential Mediators of Myocardial Depression.- Immunological Mediators in Arteriosclerosis.- Transplant Associated Coronary Artery Disease.- Role of Ischemia/Reperfusion Injury in Organ Transplantation.- The Role of NO Synthases in Immunological Diseases: Importance for Left Ventricular Function.- The Role of the Endothelium in Atherosclerosis.- Immune and Inflammatory Responses in the Human Atherosclerotic Plaque.- Inflammation in Acute Coronary Syndromes.- Immunological Mechanisms in Myocardial Reperfusion Injury.- Metalloproteinases and Atherosclerotic Plaque Rupture.- Potential Role of Human Cytomegalovirus and Its Interaction with p53 in Coronary Restenosis.- Therapeutic Approaches for Immune-Mediated Cardiovascular Diseases.- Protective Effects of Monoclonal Antibodies to Cell Adhesion Glycoproteins in Models of Cardiac Reperfusion Injury and Leukocyte/Vascular Responses.- Prevention of Arterial Restenosis of Rapamycin and Mycophenolate Mofetil: A New Role for Novel Immunosuppressants in the Prevention of Post-Balloon Angioplasty Restenosis?.- Treatment of Inflammatory Cardiomyopathy with Corticosteroids.- The Genetics of Dilated Cardiomyopathy.- Mechanisms of Allograft Rejection and Therapeutic Options.