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Tight Junctions: Classification, Structure and Functions compiles current knowledge sourced from pre-clinical and clinical research and discusses, in detail, the role of tight junctions in different chronic liver diseases. The molecular structure of tight junction transmembrane proteins and their contribution to the function and regulation of epithelial permeability is also discussed. In closing, the collection explores the molecular mechanisms of endometrial cancer progression, induced by the decrease in epithelial barrier function arising from alterations in the expression and localization of the tricellular tight junction proteins.
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