Tissue-Specific Estrogen Action (eBook, PDF)

Novel Mechanisms, Novel Ligands, Novel Therapies
Redaktion: Korach, Kenneth S.; Wintermantel, Tim

• Format: PDF

Produktbeschreibung

Current molecular understanding of estrogen action has greatly profited from advances in molecular cell biology. These advances, and their implications for clinical use, were discussed by leading researchers from industry and academia during an international symposium held in Berlin, 1-3 March 2006 and are featured in this volume.

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Produktdetails

• Verlag: Springer Berlin Heidelberg
• Seitenzahl: 181
• Erscheinungstermin: 16. Mai 2007
• Englisch
• ISBN-13: 9783540495482
• Artikelnr.: 37370351

Inhaltsangabe

Interfering with the Dynamics of Estrogen Receptor-Regulated Transcription.- Actions of Estrogen and Estrogen Receptors in Nonclassical Target Tissues.- Genetic Dissection of Estrogen Receptor Signaling In Vivo.- Of Mice and Men: The Many Guises of Estrogens.- Estradiol Action in Atherosclerosis and Reendothelialization.- Functional Effects and Molecular Mechanisms of Subtype-Selective ER? and ER? Agonists in the Cardiovascular System.- Pathogenesis and Therapy of Rheumatoid Arthritis.- The Role of ER? and ER? in theProstate: Insights from Genetic Models and Isoform-Selective Ligands.- Preclinical Characterization of Selective Estrogen Receptor ? Agonists: New Insights into Their Therapeutic Potential.- Exploiting Nongenomic Estrogen Receptor-Mediated Signaling for the Development of Pathway-Selective Estrogen Receptor Ligands.

Rezensionen

From the reviews:

"This summation of a symposium discusses some of the new research developments and estrogen-receptor based therapies that are being tested in the laboratory and in current use. ... It is written for researchers, physician scientists, and those interested in estrogen receptor interactions at a molecular level. Hopefully, it can also stimulate interest in and future research by graduate students or clinical/basic researchers." (Amber R. Cooper, Doody's Review Service, January 2008)