TNF Receptor Associated Factors (TRAFs) (eBook, PDF)

Redaktion: Wu, Hao

• Format: PDF

Produktbeschreibung

This book is the only literature that is entirely devoted to TNF Receptor Associated Factors (TRAFs). Almost every aspect of TRAF signaling is covered. The book is intended for a wide audience, including researchers in the field of TRAF signaling and students and postdoctoral fellows learning cell biology and cell signal transduction. This exciting new volume is up-to-date on the most recent advances in TRAF signal transduction.

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Produktdetails

• Verlag: Springer New York
• Seitenzahl: 206
• Erscheinungstermin: 15. Dezember 2007
• Englisch
• ISBN-13: 9780387706306
• Artikelnr.: 37288479

Autorenporträt

Hao Wu, Cornell University Weill Medical College, New York, NY, USA

Inhaltsangabe

Phylogeny of the TRAF/MATH Domain.- TRAF1 and Its Biological Functions.- Physiological Roles and Mechanisms of Signaling by TRAF2 and TRAF5.- TRAF3 and Its Biological Function.- TRAF4, the Unique Family Member.- Characteristics and Biological Functions of TRAF6.- Ubiquitination and TRAF signaling.- Structural Revelations of TRAF2 Function in TNF Receptor Signaling Pathway.- Protein-Protein Interactions in TRAF3.- Molecular Basis for the Unique Specificity of TRAF6.- TRAF Proteins in CD40 Signaling.- TRAFs in RANK Signaling.- The LT?R Signaling Pathway.- LMP1 TRAFficking Activates Growth and Survival pathways.- Targeting TRAFs for Therapeutic Intervention.