Steve Caplan

Today's Curiosity is Tomorrow's Cure (eBook, PDF)

The Case for Basic Biomedical Research

• Format: PDF

Produktbeschreibung

Basic curiosity-driven biomedical science has delivered many of today's most significant medical advances.

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Produktdetails

• Verlag: Taylor & Francis
• Seitenzahl: 224
• Erscheinungstermin: 9. November 2021
• Englisch
• ISBN-13: 9781000470970
• Artikelnr.: 62709900

Autorenporträt

Steve Caplan is Professor in the Department of Biochemistry and Molecular Biology at the University of Nebraska Medical Center, Omaha, NE. He also serves at the Director, UNMC Advanced Microscopy Core Facility at the University of Nebraska Medical Center and as Vice Chair for Administrative Affairs, Dept. of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha. His basic research has been consistently supported for more than a decade by the National Institutes of Health as well as other granting agencies. He has been the author or co-author of dozens of scientific peer reviewed journal articles.

Inhaltsangabe

Acknowledgments. Preface. Introduction. The Birth of Genetics. The Dawn of
DNA. DNA as the Transforming Principle. The Structure of DNA Lends Itself
to a Model for Its Duplication. Tying It All Together: tRNA, mRNA,
Ribosomes, and the Genetic Code. The Practicality of PCR: The Technology
that Drove the Biotechnology and the Molecular Biology Revolution. Genetic
Engineering and Beyond: From Animal Models to Silencing RNA. CRISPR, a New
Technique for Gene Editing. Connecting Mutations to Disease: Abnormal
Proteins as a Cause of Disease. Penicillin: The Dawn of a New Age of
Antibiotics. Easy to Stomach: The Gutsy Discovery that Helicobacter pylori
Causes Ulcers. Insulin: A Hormone Controlling Metabolism. The Stem Cell:
The Mother of All Cells. Antibodies: A New Way to Harness the Immune
Response. Onto Oncogenes: Discovering the Molecular Basis of Cancer. The
Age of Angiogenesis: Discovering How Blood Vessels Are Generated. Telling
the Tale of the Telomere and Telomerase: The End of the End-Replication
Problem. The Primary Cilium: Novel Functions for an Old Organelle. The
Discovery of the Golgi Complex: A Pivotal Organelle with Multiple
Functions. The Lysosome: A Trash Bin and End of the Road for Many Cellular
Molecules. The Ubiquitin-Proteasomal Pathway: Targeted Protein Degradation
and More. Receptor-Mediated Endocytosis: Gateway to the Cell. Mitochondria:
The Metabolic Powerhouse of the Cell. The Light at the End of the Tunnel:
Discovery of the Green Fluorescent Protein. Conclusions. Glossary of Terms.
Bibliography. Index.