Toxoplasma Gondii (eBook, ePUB)

The Model Apicomplexan - Perspectives and Methods
Redaktion: Weiss MD, Mph; Kim MD, Kami

• Format: ePub

Produktbeschreibung

Toxoplasma gondii: The Model Apicomplexan - Perspectives and Methods, Third Edition, reflects significant advances in the field in the last five years, including new information on the genomics, epigenomics and proteomics of T. gondii, along with a new understanding of the population biology and genetic diversity of this organism. This edition expands information on the effects of T. gondii on human psychiatric disease and new molecular techniques, such as CAS9/CSPR. T gondii remains the best model system for studying the entire Apicomplexa group of protozoans, which includes Malaria, making this new edition essential for a broad group of researchers and scientists.

• Presents a complete review of molecular and cellar biology and immunology of Toxoplasma gondii combined with methods and resources for working with this pathogen
• Provides a single source reference for a wide range of scientists and physicians working with this pathogen, including parasitologists, cell and molecular biologists, veterinarians, neuroscientists, physicians and food scientists
• Covers recent advances in the genomics, related bioinformatics analysis, epigenomics, gene regulation, genetic manipulation and proteomics of T. gondii
• Details advances in the molecular and cellular biology and immunology of Toxoplasma, and in the epidemiology, diagnosis, treatment and prevention of toxoplasmosis

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Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 1242
• Erscheinungstermin: 28. Februar 2020
• Englisch
• ISBN-13: 9780128150429
• Artikelnr.: 61688372

Inhaltsangabe

1. The History and Life Cycle of Toxoplasma gondii
2. The Ultrastructure of Toxoplasma gondii
3. Molecular Epidemiology and Population Structure of Toxoplasma gondii
4. Human Toxoplasma Infection¿
5. Ocular Disease due to Toxoplasma gondii
6. Toxoplasmosis in Wild and Domestic Animals
7. Toxoplasma Animal Models and Therapeutics
8. Biochemistry and Metabolism of Toxoplasma gondii: Lipids and Nutrient
Acquisition
9. Biochemistry and Metabolism of Toxoplasma gondii: Nucleotide and Amino
Acid Metabolism
10. Biochemistry and Metabolism of Toxoplasma gondii: Carbohydrates and
Metabolomics
11. The Apicoplast and Mitochondrion of Toxoplasma gondii
12. Calcium Storage and Homeostasis in Toxoplasma gondii
13. Signaling Networks in Toxoplasma gondii
14. Toxoplasma Secretory Proteins (Micronemes, Rhoptries, Dense Granules)
15. Toxoplasma Secretory Pathway, Intracellular Trafficking, and Autophagy
16. The Toxoplasma Cytoskeleton: Structures, Proteins and Processes (Need
to include actin)
17. Toxoplasma Host Effectors in Cell Interactions
18. Bradyzoite and Sexual Stage Development
19. Development and Application of Classical Genetics in Toxoplasma gondii
20. Genetic Manipulation of Toxoplasma gondii
21. Epigenetic and Genetic Factors that Regulate Gene Expression in
Toxoplasma gondii
22. Proteomics and Post Translational Protein Modifications in Toxoplasma
gondii
23. ToxoDB: An Integrated Functional Genomic Resource for Toxoplasma and
Other Sarcocystidae
24. Cerebral Toxoplasmosis: Pathogenesis, Host Resistance and Behavioral
Consequences
25. Innate Immunity to Toxoplasma gondii
26. Adaptive Immunity and Genetics of the Host Immune Response