Transporters as Targets for Drugs (eBook, PDF)

Redaktion: Napier, Susan; Bingham, Matilda

• Format: PDF

Produktbeschreibung

M. Bingham . S. Napier: Overview: Transporters as Targets for Drug Discovery

I. Sylte . A.W. Ravna . G. Sager . S.G. Dahl: Membrane Transporters: Structure, Function and Targets for Drug Design

G.A. Whitlock . M.D. Andrews . A.D. Brown . P.V Fish . A. Stobie . F. Wakehut: Design of Monoamine Reuptake Inhibitors - SSRIs, SNRIs and NRIs

A. Hauck Newman . J.L. Katz: Atypical Dopamine Uptake Inhibitors that Provide Clues About Cocaine's Mechanism at the Dopamine Transporter

Z. Chen . J. Yang . P. Skolnick: The Design, Synthesis and Structure-Activity Relationship of Mixed Serotonin, Norepinephrine and Dopamine Uptake Inhibitors

G. Antoni . J. Sörensen . H. Hall: Molecular Imaging of Transporters with Positron Emission Tomography

R. Bridges . S.A. Patel: Pharmacology of Glutamate Transport in the CNS: Substrates and Inhibitors of Excitatory Amino Acid Transporters (EAATs) and the Glutamate/Cystine Exchanger System xc

R. Gilfillan . J. Kerr G. . Walker . G. Wishart: Glycine Transporters and Their Inhibitors

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Produktdetails

• Verlag: Springer Berlin Heidelberg
• Seitenzahl: 254
• Erscheinungstermin: 5. Mai 2009
• Englisch
• ISBN-13: 9783540879121
• Artikelnr.: 53152553

Inhaltsangabe

Overview: Transporters as Targets for Drug Discovery.- Membrane Transporters: Structure, Function and Targets for Drug Design.- Design of Monoamine Reuptake Inhibitors: SSRIs, SNRIs and NRIs.- Atypical Dopamine Uptake Inhibitors that Provide Clues About Cocaine's Mechanism at the Dopamine Transporter.- The Design, Synthesis and Structure-Activity Relationship of Mixed Serotonin, Norepinephrine and Dopamine Uptake Inhibitors.- Molecular Imaging of Transporters with Positron Emission Tomography.- Pharmacology of Glutamate Transport in the CNS: Substrates and Inhibitors of Excitatory Amino Acid Transporters (EAATs) and the Glutamate/Cystine Exchanger System x c ?.- Glycine Transporters and Their Inhibitors.