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Rare gynecological cancers kill all too commonly Gynecological cancer is a frightening prospect for women. It is terrifying also for physicians who need, but often can't find, guidance on how to investigate and appropriately treat the tumors. Rare cancers provide greater challenges as information can be harder to find and more difficult to verify. Rare Gynecologic Cancers: Diagnosis and Management brings together all you need to know on these life-threatening diseases. Straightforward summaries of pathophysiologic processes lead to the investigations that will improve your diagnostic accuracy.…mehr
Rare gynecological cancers kill all too commonly Gynecological cancer is a frightening prospect for women. It is terrifying also for physicians who need, but often can't find, guidance on how to investigate and appropriately treat the tumors. Rare cancers provide greater challenges as information can be harder to find and more difficult to verify. Rare Gynecologic Cancers: Diagnosis and Management brings together all you need to know on these life-threatening diseases. Straightforward summaries of pathophysiologic processes lead to the investigations that will improve your diagnostic accuracy. This provides the basis for you to identify effective treatment strategies for your patients. Written by a world-leading team of Editors and Authors and covering cancers of the * Ovaries * Uterus * Vulva * Vagina * Cervix Rare Gynecologic Cancers: Diagnosis and Management will guide you to the best life-saving treatment for your patients.
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Autorenporträt
John O. Schorge, MD, Associate Professor of Obstetrics and Gynecology, Harvard Medical School, Boston and Chief, Gynecologic Oncology, OB/GYN, Massachusetts General Hospital. Robert H Young, MD, Robert E. Scully Professor of Pathology, Harvard Medical School, Boston. Michael J Birrer, MD, PhD, Professor, Department of Medicine, Harvard Medical School. Marcela del Carmen, MD, Associate Professor, Department of Obstetrics, Gynecology and Reproductive Biology, Harvard Medical School and Associate Professor, Gynecologic Oncology, Massachusetts General Hospital.
Inhaltsangabe
List of Contributors vi Preface viii Part 1 General Principles 1 1 Molecular Targets in Gynecologic Cancers 3 Whitfield Growdon, Rosemary Foster, and Bo Rueda 2 Imaging of Rare Gynecologic Tumors 18 Hima B. Prabhakar and Dinushi S. Perera 3 Pathology Overview of Rare Gynecologic Tumors 35 Robert H. Young Part 2 Rare Ovarian Cancers 51 4 Ovarian Clear Cell Carcinoma 53 Rachel M. Clark and John O. Schorge 5 Mucinous Epithelial Ovarian Cancer 64 Marcela G. del Carmen 6 Pseudomyxoma Peritonei 70 Leslie S. Bradford and Annekathryn Goodman 7 Squamous Cell Carcinoma of the Ovary 81 Ryan J. Spencer and Laurel W. Rice 8 Endometriosis-Associated Ovarian Cancer 94 Leslie A. Garrett and Marcela G. del Carmen 9 Carcinosarcoma of the Ovary 109 J. Alejandro Rauh-Hain and Marcela G. del Carmen 10 Malignant Germ Cell Tumors of the Ovary 120 Marcela G. del Carmen 11 Malignant Sex Cord-Stromal Tumors of the Ovary 132 Marcela G. del Carmen and Richard T. Penson 12 Small Cell and Neuroendocrine Cancers of the Ovary 139 Ariel A. Kaphan and Cesar M. Castro 13 Carcinoid Tumors of the Ovary 148 Michael J. Worley Jr., and Michael G. Muto Part 3 Rare Uterine Cancers 157 14 Uterine Carcinosarcoma 159 Premal H. Thaker and Don S. Dizon 15 Uterine Leiomyosarcoma 167 Marcela G. del Carmen 16 Mucinous Tumors of the Uterine Corpus 178 Rachel M. Clark and Marcela G. del Carmen 17 Uterine Clear Cell Carcinoma 186 J. Alejandro Rauh-Hain, Alexander B. Olawaiye, and David M. Boruta 18 Updates on the Management of Uterine Serous Carcinoma 195 Amanda Ramos and Amanda Nickles Fader 19 Endometrial Stromal Sarcomas 205 Kathleen M. Schmeler, J. Alejandro Rauh-Hain, and Marcela G. del Carmen Part 4 Rare Cancers of the Cervix, Vulva and Vagina 217 20 Small Cell Neuroendocrine Carcinoma of the Cervix 219 Olivia W. Foley, Leslie S. Bradford, and Marcela G. del Carmen 21 Primary Malignant Melanoma of the Vagina and Vulva 228 Alexander B. Olawaiye 22 Sarcomas of the Vulva and Vagina 236 Rachel M. Clark, J. Alejandro Rauh-Hain, and Marcela G. del Carmen 23 Gestational Trophoblastic Disease 245 Whitfield Growdon Index 260
List of Contributors vi Preface viii Part 1 General Principles 1 1 Molecular Targets in Gynecologic Cancers 3 Whitfield Growdon, Rosemary Foster, and Bo Rueda 2 Imaging of Rare Gynecologic Tumors 18 Hima B. Prabhakar and Dinushi S. Perera 3 Pathology Overview of Rare Gynecologic Tumors 35 Robert H. Young Part 2 Rare Ovarian Cancers 51 4 Ovarian Clear Cell Carcinoma 53 Rachel M. Clark and John O. Schorge 5 Mucinous Epithelial Ovarian Cancer 64 Marcela G. del Carmen 6 Pseudomyxoma Peritonei 70 Leslie S. Bradford and Annekathryn Goodman 7 Squamous Cell Carcinoma of the Ovary 81 Ryan J. Spencer and Laurel W. Rice 8 Endometriosis-Associated Ovarian Cancer 94 Leslie A. Garrett and Marcela G. del Carmen 9 Carcinosarcoma of the Ovary 109 J. Alejandro Rauh-Hain and Marcela G. del Carmen 10 Malignant Germ Cell Tumors of the Ovary 120 Marcela G. del Carmen 11 Malignant Sex Cord-Stromal Tumors of the Ovary 132 Marcela G. del Carmen and Richard T. Penson 12 Small Cell and Neuroendocrine Cancers of the Ovary 139 Ariel A. Kaphan and Cesar M. Castro 13 Carcinoid Tumors of the Ovary 148 Michael J. Worley Jr., and Michael G. Muto Part 3 Rare Uterine Cancers 157 14 Uterine Carcinosarcoma 159 Premal H. Thaker and Don S. Dizon 15 Uterine Leiomyosarcoma 167 Marcela G. del Carmen 16 Mucinous Tumors of the Uterine Corpus 178 Rachel M. Clark and Marcela G. del Carmen 17 Uterine Clear Cell Carcinoma 186 J. Alejandro Rauh-Hain, Alexander B. Olawaiye, and David M. Boruta 18 Updates on the Management of Uterine Serous Carcinoma 195 Amanda Ramos and Amanda Nickles Fader 19 Endometrial Stromal Sarcomas 205 Kathleen M. Schmeler, J. Alejandro Rauh-Hain, and Marcela G. del Carmen Part 4 Rare Cancers of the Cervix, Vulva and Vagina 217 20 Small Cell Neuroendocrine Carcinoma of the Cervix 219 Olivia W. Foley, Leslie S. Bradford, and Marcela G. del Carmen 21 Primary Malignant Melanoma of the Vagina and Vulva 228 Alexander B. Olawaiye 22 Sarcomas of the Vulva and Vagina 236 Rachel M. Clark, J. Alejandro Rauh-Hain, and Marcela G. del Carmen 23 Gestational Trophoblastic Disease 245 Whitfield Growdon Index 260
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