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Vaccinology and Methods in Vaccine Research is a combination of cutting-edge methodologies, experimental approaches and literature reviews. The book covers all aspects of vaccine development, including basic immunology (focusing on the stimulation of adaptive immunity, which is required for vaccine efficacy), approaches to vaccine design and target validation, vaccine biomanufacturer and clinical development. Existing vaccinology resources are theoretical reference books, whereas this book provides a practical handbook for use in the research lab and classroom by those working in vaccinology…mehr
Vaccinology and Methods in Vaccine Research is a combination of cutting-edge methodologies, experimental approaches and literature reviews. The book covers all aspects of vaccine development, including basic immunology (focusing on the stimulation of adaptive immunity, which is required for vaccine efficacy), approaches to vaccine design and target validation, vaccine biomanufacturer and clinical development. Existing vaccinology resources are theoretical reference books, whereas this book provides a practical handbook for use in the research lab and classroom by those working in vaccinology and training others in the field.
It is authored and edited by scientists actively engaged in vaccine research and development for day-to-day teaching/methodological advice.
Addresses how to design a vaccine for an emerging disease, from a practical point-of -view, with chapters written by scientists who are grappling with these questions
Provides new approaches to vaccine development. including vaccine targeting and virus-like-particle vaccines
Gives up-to-date information and methodologies in use for vaccine adjuvants
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Rebecca Ashfield Jenner Institute, University of Oxford (ORCRB Roosevelt Drive Oxford OX3 7DQ). BA (1st class) Oxford, DPhil Oxford, over 20 years working in field of immunotherapy and vaccine development. Currently CSO of Ducentis Biotherapeutics Ltd and Senior Project Manager at the Jenner Institute. Organiser/co-leader of several vaccinology courses in Oxford and Leiden. Edited most recent Jenner Institute triennial report. Expertise in vaccine GMP manufacture, led successful application to Innovate UK for £75M vaccine innovation and manufacturing centre, currently being built at Harwell in Oxfordshire. H=20Angus Nnamdi Oli Pharmaceutical Microbiology and Biotechnology, Nnamdi Azikiwe University (NAU), Agulu Campus (Post code 422001, Agulu, Anambra State, Nigeria). BPharm. and MPharm. UNN, DPhil NAU and a DPharm. University of Benin, Nigeria. Currently a Senior Lecturer with over 8 years' experience. Author of several articles in peer-reviewed journals indexed in Pubmed, Web of Science and Scopus. Current research interests/career goals are Infection and immunology of infectious diseases with emphasis of viral and bacterial infections, development of effective vaccines with strong antibody and T lymphocytes effect or responses against the infections, Pharmaceutical Quality Systems and Clinical vaccinology. H: 5
Inhaltsangabe
1. Immunology and the Concept of Vaccination Rebecca Chukwuanukwu, A. Ehiaghe, A. Rowaiye and Angus Nnamdi Oli 2. Vaccine Types and Reverse Vaccinology A. Rowaiye and Angus Nnamdi Oli 3. Dendritic Cells as Vaccine Targets P. Aondona, F. Iseghohi, A. Rowaiye and Angus Nnamdi Oli 4. Vaccine Development: From the Laboratory to the Field Nana Efua Andoh and Linda Onyeka Anagu 5. Immunopeptidomics for the Identification of T cell Vaccine Targets P. Bettencourt and C. Barbosa 6. Virus Like Particle Vaccines Ahmed M. Salman, Ekta Mukhopadhyay and Adrian Hill 7. Approaches to Cancer Vaccination Ezinne Janefrances Nwonu 8. Vaccines against SARS-CoV-2 K. Ewer and Andrés Noé 9. Adjuvants, Immunomodulators and Adaptogens Anita Milicic, M. Ugwu, Sabina Górska, Agnieszka Razim, M. Luchner, Slavcho Mrenoshki, H. Kefei, G. Corby, A. Thakur, Sveinbjorn Gizurarson, J. Fergusson, Dennis Christensen, S. Ercelen, S. Longet, B. Morein, E. Lindblad and S. Reinke 10. GMP Manufacture and Quality Control Chapter Rebecca Ashfield 11. Testing Vaccines: Essential Steps in Clinical Trial Design Julia Marshall
1. Immunology and the Concept of Vaccination Rebecca Chukwuanukwu, A. Ehiaghe, A. Rowaiye and Angus Nnamdi Oli 2. Vaccine Types and Reverse Vaccinology A. Rowaiye and Angus Nnamdi Oli 3. Dendritic Cells as Vaccine Targets P. Aondona, F. Iseghohi, A. Rowaiye and Angus Nnamdi Oli 4. Vaccine Development: From the Laboratory to the Field Nana Efua Andoh and Linda Onyeka Anagu 5. Immunopeptidomics for the Identification of T cell Vaccine Targets P. Bettencourt and C. Barbosa 6. Virus Like Particle Vaccines Ahmed M. Salman, Ekta Mukhopadhyay and Adrian Hill 7. Approaches to Cancer Vaccination Ezinne Janefrances Nwonu 8. Vaccines against SARS-CoV-2 K. Ewer and Andrés Noé 9. Adjuvants, Immunomodulators and Adaptogens Anita Milicic, M. Ugwu, Sabina Górska, Agnieszka Razim, M. Luchner, Slavcho Mrenoshki, H. Kefei, G. Corby, A. Thakur, Sveinbjorn Gizurarson, J. Fergusson, Dennis Christensen, S. Ercelen, S. Longet, B. Morein, E. Lindblad and S. Reinke 10. GMP Manufacture and Quality Control Chapter Rebecca Ashfield 11. Testing Vaccines: Essential Steps in Clinical Trial Design Julia Marshall
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