Vasopressin and Oxytocin: From Genes to Clinical Applications (eBook, PDF)

Redaktion: Poulain, D.; Theodosis, D.; Oliet, S.

• Format: PDF

Produktbeschreibung

The articles comprising this volume were first presented at the World Congress on Neurohypophysial Hormones held in Bordeaux, France on September 8-12, 2001. This conference brought together more than 170 scientists from 18 countries who belong to the different fields of interest representing research in the hypothalamo-neurohypophysial system.

Two neurohypophysial neurohormones, oxytocin and vasopressin, exert a variety of central and peripheral actions and thus involve different scientific domains, which too often, even today, do not always find the appropriate occasion to interact. This volume is composed of chapters dealing with topics varying from basic and clinical neurosciences and neuroendocrinology, to reproductive, renal, cardiovascular physiology and pathology. It encompasses all areas of current neurohypophysial research and should be of vital interest as an integrative reference volume to specialized investigators and as an excellent introductory text to students, scientists and clinicians not yet closely familiar with the field. To ensure novelty and to make sure that all topics of current importance were covered, plenary and symposium speakers as well as poster presentations concentrated on recent advances made in the last few years.

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Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 392
• Erscheinungstermin: 24. Oktober 2002
• Englisch
• ISBN-13: 9780080522821
• Artikelnr.: 38117058

Inhaltsangabe

List of contributors. Preface. 1. The magnocellular neuronal phenotype:
cell-specific gene expression in the hypothalamo-neurohypophysial system
(H. Gainer et al.). 2. Estrogen modulates oxytocin gene expression in
regions of the rat supraoptic and paraventricular nuclei that contain
estrogen receptor-&bgr; (P.J. Shughrue, T.L. Dellovade, I. Merchenthaler).
3. Short term modulation of GABA-receptor in the adult female rat
(A.B. Brussaard, J.J. Koksma). 4. Cholesterol and steroid hormones:
modulators of oxytocin receptor function
(G. Gimpl et al.). 5. Central vasopressin systems and steroid hormones (A.
Kalsbeek, I.F. Palm, R.M. Buijs). 6. Regulation of renal salt and water
transporters during vasopressin escape (C.A. Ecelbarger et al.). 7.
Stretch-inactivated cation channels: cellular targets for modulation of
osmosensitivity in supraoptic neurons (C.W. Bourque, D.L. Voisin, Y.
Chakfe). 8. Glial cells in the hypothalamo-neurohypophysial system: key
elements of the regulation of neuronal electrical and secretory activity
(N. Hussy). 9. Functional synaptic plasticity in hypothalamic magnocellular
neurons (J.G. Tasker, S. Di, C. Boudaba). 10. Post synaptic GABA receptors
in supraoptic oxytocin and vasopressin neurons (J.E. Stern, Y. Li, D.S.
Richards). 11. Neurohypophyseal hormones in the integration of
physiological responses to immune challenges
(K.J. Kovács). 12. Involvement of the brain oxytocin system in stress
coping: interactions with the hypothalamo-pituitary-adrenal axis (I.D.
Neumann). 13. Expression of human vasopressin and oxytocin receptors in
Escherichia coli
(B. Mouillac et al.). 14. Molecular pharmacology and modeling of
vasopressin receptors (M. Thibonnier et al.). 15. Nonpeptide vasopressin
receptor antagonists: development of selective and orally-active V, V and V
receptor ligands (C. Serradeil-Le Gal et al.). 16. Rat vasopressin mRNA: a
model system to characterize cis-acting elements and trans-acting factors
involved in dendritic mRNA sorting (E. Mohr et al.). 17. Dendritic action
potentials in magnocellular neurons (J.S. Bains). 18. Modulation of
synaptic transmission by oxytocin and vasopressin in the supraoptic nucleus
(S.B. Kombian et al.). 19. The active role of dendrites in the regulation
of magnocellular neurosecretory cell behavior (M. Ludwig et al.). 20.
Cardiovascular regulation of supraoptic vasopressin neurons (J.T.
Cunningham et al.). 21. The central vasopressinergic system in experimental
left ventricular hypertrophy and dysfunction (F. Muders et al.). 22.
Cardiovascular effects of oxytocin (M. Petersson). 23. Treatment of the
diabetic patient: focus on cardiovascular and renal risk reduction (K.C.
Abbott, G.L.K. Bakris). 24. Oxytocin in parturition of guinea pigs, humans
and other species
(J.-C. Schellenberg). 25. Oxytocin, vasopressin and atrial natriuretic
peptide control body fluid homeostasis by action on their receptors in
brain, cardiovascular system and kidney
(S.M. McCann et al.). 26. Positive and negative regulators of the
vasopressin gene promoter in small cell lung cancer (J.M. Coulson). 27. The
vasopressin receptor of corticotroph pituitary cells (P. René, Y. De
Keyzer). 28. Involvement of oxytocin and vasopressin in the pathophysiology
of preterm labor and primary dysmenorrhea (M. Åkerlund). Subject Index.