Vertebrate Eye Development (eBook, PDF)

Redaktion: Fini, M. Elizabeth

• Format: PDF

Produktbeschreibung

The power of molecular genetics has recently returned the discipline of Developmental Biology to its original position at the forefront of biological research. The vertebrate eye was one of the classic embryologic models in the early 1900s. Within the last decade of the 20th century, a return to some of the old questions with the new approaches has put eye development back into the limelight. This book provides an up-to-date and comprehensive overview of the field. The latest advances in delineating genetic hierarchies for eye development in animals are discussed, as well as their relationship to congenital disorders of the eye which affect humans. Since studies in Drosophila have provided significant insight, chapters on this invertebrate model are included. In addition, a number of related areas are discussed which are unique to this book: developmental anatomy of the eye from the perspective of its optical function, recent advances in understanding how the retina connects to the brain, the role of extracellular matrix and cell adhesion molecules in eye development, and two chapters on eye regeneration in amphibians and fish.

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Produktdetails

• Verlag: Springer Berlin Heidelberg
• Seitenzahl: 288
• Erscheinungstermin: 7. September 2012
• Englisch
• ISBN-13: 9783540468264
• Artikelnr.: 53328218

Inhaltsangabe

Overview.- Vertebrate Eye Development and Refractive Function: An Overview.- Early Pattern Formation.- Pax6 and the Genetic Control of Early Eye Development.- Early Retinal Development in Drosophila.- Embryonic Induction.- Induction of the Lens.- Retinal Differentiation.- Molecular Control of Cell Diversification in the Vertebrate Retina.- Cell Fate Specification in the Drosophila Retina.- Roles of the Extracellular Matrix in Retinal Development and Maintenance.- Adhesive Events in Retinal Development and Function: The Role of Integrin Receptors.- Formation of Neural Pathways for Vision.- Connecting the Eye with the Brain: The Formation of the Retinotectal Pathway.- Regeneration.- Regeneration of the Lens in Amphibians.- How the Neural Retina Regenerates.- Genetic Models.- Mouse Mutants for Eye Development.- Genetic Analysis of Eye Development in Zebrafish.