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Veterinary Pharmacology and Therapeutics, Tenth Edition is a fully updated and revised version of the gold-standard reference on the use of drug therapy in all major veterinary species. * Provides current, detailed information on using drug therapies in all major domestic animal species * Organized logically by drug class and treatment indication, with exhaustive information on the rational use of drugs in veterinary medicine * Includes extensive tables of pharmacokinetic data, products available, and dosage regimens * Adds new chapters on pharmaceutics, ophthalmic pharmacology, food animal…mehr
Veterinary Pharmacology and Therapeutics, Tenth Edition is a fully updated and revised version of the gold-standard reference on the use of drug therapy in all major veterinary species. * Provides current, detailed information on using drug therapies in all major domestic animal species * Organized logically by drug class and treatment indication, with exhaustive information on the rational use of drugs in veterinary medicine * Includes extensive tables of pharmacokinetic data, products available, and dosage regimens * Adds new chapters on pharmaceutics, ophthalmic pharmacology, food animal pharmacology, and aquatic animal pharmacology * Includes access to a companion website with the figures from the book in PowerPoint
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Autorenporträt
The editors Jim E. Riviere, DVM, PhD, DSc (hon), ATS, is The MacDonald Chair in Veterinary Medicine, University Distinguished Professor, Kansas Bioscience Eminent Scholar, and Director, Institute of Computational Comparative Medicine at Kansas State University in Manhattan, Kansas, USA. He is also a Distinguished Professor Emeritus at North Carolina State University in Raleigh, North Carolina, USA. Mark G. Papich, DVM, MS, Diplomate ACVCP, has the Burroughs Wellcome Professorship in Veterinary Pharmacology and is a Professor of Clinical Pharmacology, Department of Molecular Biomedical Sciences, College of Veterinary Medicine at North Carolina State University in Raleigh, North Carolina, USA.
Inhaltsangabe
Contributors xiii
Preface xix
About the Companion Website xxi
Section ?I Principles of Pharmacology 1
Veterinary Pharmacology: An Introduction to the Discipline 3 Jim E. Riviere and Mark G. Papich
Absorption, Distribution, Metabolism, and Elimination 8 Jim E. Riviere
Pharmacokinetics 41 Jim E. Riviere
Mechanism of Drug Action and Pharmacokinetics/ Pharmacodynamics Integration in Dosage Regimen Optimization for Veterinary Medicine 65 Pierre-Louis Toutain
Principles of Pharmaceutics and Veterinary Dosage Forms 87 Raafat M. Fahmy and Marilyn N. Martinez
Section ?f Drugs Acting on the Autonomic Nervous System 111
Introduction to the Autonomic Nervous Systemand Autonomic Pharmacology 113 Joshua A. Rowe, RoseM.McMurphy, Barbara J. Lutjemeier, andMichael J. Kenney
Adrenergic Receptor Agonists and Antagonists 131 Rose M.McMurphy, Elizabeth G. Davis, Amy J. Rankin, Daniel A. Frese, Barbara J. Lutjemeier, and Michael J. Kenney
Cholinergic Pharmacology: Autonomic Drugs 151 RoseM.McMurphy, Elizabeth G. Davis, Amy J. Rankin,Marjory A. Artzer, Barbara J. Lutjemeier, andMichael J. Kenney
Section ?g Anesthetics and Analgesics, and Drugs Acting on the Central Nervous System 165
Introduction to Drugs Acting on the Central Nervous Systemand Principles of Anesthesiology 167 Peter J. Pascoe and Eugene P. Steffey
Neuromuscular Blocking Agents 194 Diane E.Mason and Christopher L. Norkus
Inhalation Anesthetics 216 Robert J. Brosnan and Eugene P. Steffey
Injectable Anesthetic Agents 247 Lysa P. Posner
Opioid Analgesic Drugs 281 Butch KuKanich andMark G. Papich
Sedatives and Tranquilizers 324 Lysa P. Posner
Local Anesthetics 369 Thomas W. Vickroy
Euthanizing Agents 387 Anna Hampton
Anticonvulsant Drugs 395 Mark G. Papich
Drugs Affecting Animal Behavior 416 Margaret E. Gruen, Barbara L. Sherman, and Mark G. Papich
Section ?h Autacoids and Antiinflammatory Drugs 449
Histamine, Serotonin, and their Antagonists 451 Wolfgang B¨aumer
Analgesic, Antiinflammatory, Antipyretic Drugs 467 Peter Lees
Section ?i Drugs Acting on the Cardiovascular System 501
Digitalis, Positive Inotropes, and Vasodilators 503 Clarke E. Atkins and Marisa K. Ames
Antiarrhythmic Agents 537 Kathryn M. Meurs and Jim E. Riviere
Section ?j Drugs Affecting Renal Function and Fluid-Electrolyte Balance 553
Principles of Acid-Base Balance: Fluid and Electrolyte Therapy, Blood Substitutes 555 Maya M. Scott-Garrard, Melisa Rosenthal, and Deborah T. Kochevar
Diuretics and Renal Pharmacology 593 Butch Kukanich and Deborah T. Kochevar
Section ?k Drugs Acting on Blood and Blood Elements 623
Anticoagulant, Antiplatelet, and Hemostatic Drugs 625 Mark G. Papich
Section ?l Endocrine Pharmacology 647
Hypothalamic and Pituitary Hormones 649 Srujana Rayalam,Margarethe Hoenig, and Duncan C. Ferguson
Hormones Affecting Reproduction 674 Wolfgang B¨aumer, C. Scott Bailey, and John Gadsby
Thyroid Hormone and Antithyroid Drugs 691 Duncan C. Ferguson
Glucocorticoids, Mineralocorticoids, and Adrenolytic Drugs 729 Duncan C. Ferguson and Margarethe Hoenig
Veterinary Pharmacology: An Introduction to the Discipline 3 Jim E. Riviere and Mark G. Papich
Absorption, Distribution, Metabolism, and Elimination 8 Jim E. Riviere
Pharmacokinetics 41 Jim E. Riviere
Mechanism of Drug Action and Pharmacokinetics/ Pharmacodynamics Integration in Dosage Regimen Optimization for Veterinary Medicine 65 Pierre-Louis Toutain
Principles of Pharmaceutics and Veterinary Dosage Forms 87 Raafat M. Fahmy and Marilyn N. Martinez
Section ?f Drugs Acting on the Autonomic Nervous System 111
Introduction to the Autonomic Nervous Systemand Autonomic Pharmacology 113 Joshua A. Rowe, RoseM.McMurphy, Barbara J. Lutjemeier, andMichael J. Kenney
Adrenergic Receptor Agonists and Antagonists 131 Rose M.McMurphy, Elizabeth G. Davis, Amy J. Rankin, Daniel A. Frese, Barbara J. Lutjemeier, and Michael J. Kenney
Cholinergic Pharmacology: Autonomic Drugs 151 RoseM.McMurphy, Elizabeth G. Davis, Amy J. Rankin,Marjory A. Artzer, Barbara J. Lutjemeier, andMichael J. Kenney
Section ?g Anesthetics and Analgesics, and Drugs Acting on the Central Nervous System 165
Introduction to Drugs Acting on the Central Nervous Systemand Principles of Anesthesiology 167 Peter J. Pascoe and Eugene P. Steffey
Neuromuscular Blocking Agents 194 Diane E.Mason and Christopher L. Norkus
Inhalation Anesthetics 216 Robert J. Brosnan and Eugene P. Steffey
Injectable Anesthetic Agents 247 Lysa P. Posner
Opioid Analgesic Drugs 281 Butch KuKanich andMark G. Papich
Sedatives and Tranquilizers 324 Lysa P. Posner
Local Anesthetics 369 Thomas W. Vickroy
Euthanizing Agents 387 Anna Hampton
Anticonvulsant Drugs 395 Mark G. Papich
Drugs Affecting Animal Behavior 416 Margaret E. Gruen, Barbara L. Sherman, and Mark G. Papich
Section ?h Autacoids and Antiinflammatory Drugs 449
Histamine, Serotonin, and their Antagonists 451 Wolfgang B¨aumer
Analgesic, Antiinflammatory, Antipyretic Drugs 467 Peter Lees
Section ?i Drugs Acting on the Cardiovascular System 501
Digitalis, Positive Inotropes, and Vasodilators 503 Clarke E. Atkins and Marisa K. Ames
Antiarrhythmic Agents 537 Kathryn M. Meurs and Jim E. Riviere
Section ?j Drugs Affecting Renal Function and Fluid-Electrolyte Balance 553
Principles of Acid-Base Balance: Fluid and Electrolyte Therapy, Blood Substitutes 555 Maya M. Scott-Garrard, Melisa Rosenthal, and Deborah T. Kochevar
Diuretics and Renal Pharmacology 593 Butch Kukanich and Deborah T. Kochevar
Section ?k Drugs Acting on Blood and Blood Elements 623
Anticoagulant, Antiplatelet, and Hemostatic Drugs 625 Mark G. Papich
Section ?l Endocrine Pharmacology 647
Hypothalamic and Pituitary Hormones 649 Srujana Rayalam,Margarethe Hoenig, and Duncan C. Ferguson
Hormones Affecting Reproduction 674 Wolfgang B¨aumer, C. Scott Bailey, and John Gadsby
Thyroid Hormone and Antithyroid Drugs 691 Duncan C. Ferguson
Glucocorticoids, Mineralocorticoids, and Adrenolytic Drugs 729 Duncan C. Ferguson and Margarethe Hoenig
