Water-Insoluble Drug Formulation (eBook, PDF)

Redaktion: Liu, Ron

• Format: PDF

Produktbeschreibung

Water-Insoluble Drug Formulation, Third Edition serves as a comprehensive reference for pharmaceutical scientists in the handling of formulation issues related to water-insoluble drugs.

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Produktdetails

• Verlag: Taylor & Francis
• Seitenzahl: 756
• Erscheinungstermin: 12. März 2018
• Englisch
• ISBN-13: 9781498729420
• Artikelnr.: 52842138

Autorenporträt

Ron Liu is CEO of AustarPharma, a pharmaceutical company based in Edison, New Jersey.

Inhaltsangabe

Introduction. Solubility Theory. Prediction of Solubility. Preformulation
Aspects of Insoluble Compounds. Water-Insoluble Drugs and Their
Pharmacokinetic Behaviors. Regulatory Aspects of Dissolution for Low
Solubility Drug Products. Formulation Strategies and Practice Used for Drug
Candidates with Water-Insoluble Properties for Toxicology, Biology, and
Pharmacology Studies in Discovery Support. Application of Complexation in
Drug Development for Insoluble Compounds. Solubilization Using Cosolvent
Approach. Emulsions, Microemulsions, and Lipid-Based Drug Delivery Systems
for Drug Solubilization and Delivery·Part I: Parenteral Applications.
Emulsions, Microemulsions, and Lipid-Based Drug Delivery Systems for Drug
Solubilization and Delivery·Part II: Oral Applications. Micellization and
Drug Solubility Enhancement. Polymeric Micelles in Water-Insoluble Drug
Delivery. Liposomes in Solubilization. Pharmaceutical Salts. Prodrugs for
Improved Solubility in Water. Particle Size Reduction. Development of Solid
Dispersion for Poorly Water-Soluble Drugs. Alteration of the Solid State of
the Drug Substances: Polymorphs, Solvates, and Amorphous Forms.
Pharmaceutical Powder Technology·ICH Q8 and Building the Pyramid of
Knowledge. Soft Gelatin Capsules Development. Oral Modified-Release Drug
Delivery for Water-Insoluble Drugs. Scalable Manufacturing of
Water-Insoluble Drug Products. Index.