This publication compiles and analyses the latest data on the international nature of studies, research and universities from Germany and major destination such as the US, the United Kingdom and Asia. The German Academic Exchange Service (DAAD) has issued this standard reference work on international mobility in the higher education sector since 2001. The spotlights in this edition explore not just the impact of the Covid-19 pandemic on international student mobility in Germany and other host countries, but also report on the academic success of international students at German universities. Moreover, the authors of the publication present figures on international students in Germany, data on mobility patterns, an overview of students' countries of origin and destination countries as well as developments in doctoral studies. Wissenschaft weltoffen integrates the international data published by the OECD and UNESCO with the national data from the Federal Statistical Office. For over 20 years, in combination with other indicators and time series, the publication has provided a valid basis for analysing and monitoring internationalisation.