Cardiovascular risk factors can develop during early age of women and manifest in middle age in most societies. There is an urgent need for implementing primary prevention approaches world wide and identifying risk women groups and areas for possible improvement and to better understand the presentation of cardiac symptoms in women, in order to facilitate diagnosis and treatment and to improve the quality of life. It is also important to raise awareness of general population and care about women CAD risk even young, about its atypical forms and the necessity of rapid and aggressive care processes. A cost-effective preventive strategy will need to focus on reducing risk factors both in the individual and in the population at large.