This book is the determination of Optimal Power for ZigBee-Based Wireless Sensor Networks. In designing WSNs, both the transmit power, network topology, and routing scheme are considered. Transmitting at lower power affect the connectivity of the network while transmitting at excessive power reduces the lifetime of nodes and increases the network interference. Thus, determining the optimal power of the nodes that will be necessary to guarantee network connectivity. In this work, a practical self-healing and self-configuring real life prototype ZigBee Wireless Mesh Sensor Networks (WMSNs) was design to evaluate the performance of IEEE 802.15.4/ZigBee. We showed that increasing the transmit power of nodes from -6dBm to 0dBm in WMSNs leads to improved packets delivery ratio and throughput improvement and the optimal power was -2dBm for the studied topology. The testbed will aid wireless sensor network designer to make an accurate decision on transmit power and mesh network topology using Ad-hoc on-demand distance vector algorithm (AODV) as the routing scheme.