School Leadership here represents the commitment shown by school leaders in understanding the urgency of the epidemic and placing interventions and strategies related to HIV/AIDS that can lead to behavioural change and positive health situation. The theoretical construct of school leadership encompasses range of interventions which could be implemented at school leadership level and was shown to interact with schools in responding to limit the impact of HIV/AIDS in education. This book prominently shows the well placement of schools in addressing the problems accrued due to HIV/AIDS epidemic if committed school leaders are appointed. The Book basically organized under five chapters dealing with an Introduction, Review of related literature, Methodology, Analysis. The objectives of this study is to examine school leadership in mitigating the impact of HIV/AIDS on the teaching- learning process and the challenges faced by schools in responding to the epidemic. The Book could be important for anybody who can read it; particularly useful for students, parents and professionals working as educational HIV/AIDS Project Managers.