Role of gene polymorphisms in Graves' disease development - Shehjar, Faheem;Laway, Bashir
46,99 €
inkl. MwSt.
Versandkostenfrei*
Versandfertig in 1-2 Wochen
payback
23 °P sammeln
  • Broschiertes Buch

This research work was conducted in the department of endocrinology; Sher-I-Kashmir Institute of Medical Sciences (SKIMS), the purpose of the research work was to find a possible association of various Single Nucleotide Polymorphisms (SNPs) in some important immunoregulatory genes with the risk of Graves' disease (GD). GD is an autoimmune disease of the thyroid gland. GD is the commonest cause of hyperthyroidism in iodine sufficient population of the world. It results from an abnormality in the immune system, which produces unique antibodies causing over production of thyroid hormones and…mehr

Andere Kunden interessierten sich auch für
Produktbeschreibung
This research work was conducted in the department of endocrinology; Sher-I-Kashmir Institute of Medical Sciences (SKIMS), the purpose of the research work was to find a possible association of various Single Nucleotide Polymorphisms (SNPs) in some important immunoregulatory genes with the risk of Graves' disease (GD). GD is an autoimmune disease of the thyroid gland. GD is the commonest cause of hyperthyroidism in iodine sufficient population of the world. It results from an abnormality in the immune system, which produces unique antibodies causing over production of thyroid hormones and glandular hyperplasia in individuals with genetic susceptibility. We found a strong association of following SNPs CTLA-4 +49 A/G, CTLA-4 CT60 A/G, FoxP3 -2383 C/T, Foxp3 -3279 C/A, IL-1b -511 T/C and IL-1b 3954 C/T with the risk of GD development.
Hinweis: Dieser Artikel kann nur an eine deutsche Lieferadresse ausgeliefert werden.
Autorenporträt
Dr. Faheem Shehjar did masters in Biotechnology from Bangalore University. He holds doctorate in Biomedical Sciences from Sher-i-Kashmir Institute of Medical Sciences (SKIMS) Srinagar. Recipient of prestigious fellowship awarded by council of scientific and industrial research (CSIR), Dr. Faheem currently works as a senior researcher at the SKIMS.