A state-of-the-art guide to building synthetic membranes for biological devices, covering their construction, measurement, and modelling.Hinweis: Dieser Artikel kann nur an eine deutsche Lieferadresse ausgeliefert werden.
William Hoiles is a Research Fellow in the Department of Electrical and Computer Engineering at the University of British Columbia, Vancouver.
Inhaltsangabe
Part I. Background: 1. Motivation and outline 2. Biochemistry for engineers: a short primer 3. Engineered artificial membranes Part II. Building Engineered Membranes, Devices and Experimental Results: 4. Formation of engineered tethered membranes 5. Ion-channel switch biosensor 6. Physiochemical membrane platforms 7. Experimental measurement methods for engineered membranes Part III. Dynamic Models for Artificial Membranes: Atoms-to-Device: 8. Reaction-rate constrained models for engineered membranes 9. Reaction-rate constrained models for the ICS biosensor 10. Diffusion constrained continuum models of engineered membranes 11. Electroporation models in engineered artificial membranes 12. Electroporation measurements in engineered membranes 13. Electrophysiological response of ion channels and cells 14. Coarse-grained molecular dynamics 15. All-atom molecular dynamics simulation models 16. Closing summary for part III: from atoms to device Appendices: Appendix A. Elementary primer on partial differential equations (PDE) Appendix B. Tutorial on coarse-grained molecular dynamics with peptides.
Part I. Background: 1. Motivation and outline 2. Biochemistry for engineers: a short primer 3. Engineered artificial membranes Part II. Building Engineered Membranes, Devices and Experimental Results: 4. Formation of engineered tethered membranes 5. Ion-channel switch biosensor 6. Physiochemical membrane platforms 7. Experimental measurement methods for engineered membranes Part III. Dynamic Models for Artificial Membranes: Atoms-to-Device: 8. Reaction-rate constrained models for engineered membranes 9. Reaction-rate constrained models for the ICS biosensor 10. Diffusion constrained continuum models of engineered membranes 11. Electroporation models in engineered artificial membranes 12. Electroporation measurements in engineered membranes 13. Electrophysiological response of ion channels and cells 14. Coarse-grained molecular dynamics 15. All-atom molecular dynamics simulation models 16. Closing summary for part III: from atoms to device Appendices: Appendix A. Elementary primer on partial differential equations (PDE) Appendix B. Tutorial on coarse-grained molecular dynamics with peptides.
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