Risk factors imply states which endanger the physical and mental development of children and, accordingly, the speech and language development. The consequences of the influence of those factors are determined by the type, intensity and duration of the events, level of the child's development at the time of exposure to those events. The analysis of the speech and language impairment of the children with the physical and mental disability has found speech and language impairments in 63.69% of the sample. The largest number of children with speech and language impairments was found in the categories of mental retardation, multiple disabilities and deafness. A large number of children were born with the problem such as too low weight and length at birth, or the pregnancy itself was irregular. The mothers of these children usually had certain complications in their pregnancies and complications at birth. Some of the children have or had HIC, HIE, hyperbilirubinemia and certain infections. The work is the result of the author's desire to provide basic information on potential risk factors that can affect speech and language development of children.