David Rasnick

The Chromosomal Imbalance Theory of Cancer

The Autocatalyzed Progression of Aneuploidy is Carcinogenesis

• Gebundenes Buch

Produktbeschreibung

The book deals with the chromosomal imbalance (aneuploidy) theory of cancer. The book explains how gene mutations are not powerful enough to cause cancer, describes how cancer is initiated and why progression takes years to decades, and accounts for the global or macroscopic characteristics that readily identify cancer. In addition, it clarifies why cancer cells often become drug resistant even to drugs they were never exposed, provides objective, quantitative measures for detecting cancer and monitoring its progression, and suggests non-toxic strategies of cancer therapy and prevention. In short, it posits that the autocatalyzed progression of aneuploidy is carcinogenesis.

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Produktdetails

• Verlag: CRC Press
• Seitenzahl: 360
• Erscheinungstermin: 20. Dezember 2011
• Englisch
• Abmessung: 240mm x 161mm x 24mm
• Gewicht: 705g
• ISBN-13: 9781578087372
• ISBN-10: 1578087376
• Artikelnr.: 34390829

Autorenporträt

Rasnick, David

Inhaltsangabe

Introducing CancerBoveri's Theory of Cancer was Ahead of its Time:
Aneuploidy theory "Got Lost".Genesis of "The Enemy Within"? Clonal cancer.
Tumorigenic retroviruses. Dominate oncogenes. Tumor suppressor genes.
Driver genes.Gene Mutation Theory of Cancer: "Carcinogens are mutagens".
Retroviral oncogenes. Are "cellular oncogenes" like retroviral oncogenes?
Updated gene mutation theory is popular but unconfirmed.The Chromosomal
Imbalance Theory of Cancer: Heuristic explanation of how chromosomal
imbalance (and not gene mutation) generates cancer phenotypes. Aneuploidy
causes chromosomal instability-the hallmark of cancer. Cancer is a
progressive somatic aneuploidy syndrome. Quantitative analysis of how
aneuploidy generates new cellular phenotypes.Theory of Chromosomal
Imbalance Solves Mysteries and Paradoxes: Carcinogenesis is dependent on
aneuploidy and not mutation. Autocatalyzed progression of aneuploidy is
carcinogenesis. Aneuploidy causes the Warburg effect by increasing ATP
demand. Balanced mitotic forces and species-specific sequential chromatid
separation may govern the rate of transformation. Cancer vaccine is very
unlikely. "Cancers are a genuine type of species"New Perspectives for
Cancer Prevention, Diagnosis and Therapy: International regulation of
aneuploidy-inducing agents. Cancer detection. Cancer therapy.Conclusion