Designed especially for students from non-physics and non-chemistry backgrounds, this book covers elementary statistical mechanics and the thermodynamics necessary to understand fundamental biophysical phenomena. The book maintains a probabilistic view throughout. It presents more than one interpretation of every phenomenon: for example, on- and off-rates are carefully explained in the context of binding affinities and connected back with a microscopic statistical picture, as well as with the standard thermodynamic description. The author explicitly explains the theory behind interpreting the physics and statistics of many experiments.…mehr
Designed especially for students from non-physics and non-chemistry backgrounds, this book covers elementary statistical mechanics and the thermodynamics necessary to understand fundamental biophysical phenomena. The book maintains a probabilistic view throughout. It presents more than one interpretation of every phenomenon: for example, on- and off-rates are carefully explained in the context of binding affinities and connected back with a microscopic statistical picture, as well as with the standard thermodynamic description. The author explicitly explains the theory behind interpreting the physics and statistics of many experiments.
Proteins Don't Know Biology. The Heart of It All: Probability Theory. Big Lessons from Simple Systems: Equilibrium Statistical Mechanics in One Dimension. Nature Doesn't Calculate Partition Functions: Elementary Dynamics and Equilibrium. Molecules Are Correlated! Multidimensional Statistical Mechanics. From Complexity to Simplicity: The Potential of Mean Force. What's Free about "Free" Energy? Essential Thermodynamics. The Most Important Molecule: Electro-Statistics of Water. Basics of Binding and Allostery. Kinetics of Conformational Change and Protein Folding. Ensemble Dynamics: From Trajectories to Diffusion and Kinetics. A Statistical Perspective on Biomolecular Simulation. Index.
Proteins Don't Know Biology. The Heart of It All: Probability Theory. Big Lessons from Simple Systems: Equilibrium Statistical Mechanics in One Dimension. Nature Doesn't Calculate Partition Functions: Elementary Dynamics and Equilibrium. Molecules Are Correlated! Multidimensional Statistical Mechanics. From Complexity to Simplicity: The Potential of Mean Force. What's Free about "Free" Energy? Essential Thermodynamics. The Most Important Molecule: Electro-Statistics of Water. Basics of Binding and Allostery. Kinetics of Conformational Change and Protein Folding. Ensemble Dynamics: From Trajectories to Diffusion and Kinetics. A Statistical Perspective on Biomolecular Simulation. Index.
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