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Oral-based diagnostics have the potential to detect systemic disease and evidence of exposure to various harmful substances, as well as provide biomarkers of health and disease status. Integration of novel approaches to oral-based diagnostics is expanding to include genomics, proteomics, bioinformatics, and nanotechnology. Improved technologies for diagnostics are resulting in more "user-friendly" methods. Efforts to translate bench assays to commercial products in the area of oral diagnostics have increased recently, as witnessed by the appearance of several new oral-based diagnostic products…mehr
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Oral-based diagnostics have the potential to detect systemic disease and evidence of exposure to various harmful substances, as well as provide biomarkers of health and disease status. Integration of novel approaches to oral-based diagnostics is expanding to include genomics, proteomics, bioinformatics, and nanotechnology. Improved technologies for diagnostics are resulting in more "user-friendly" methods. Efforts to translate bench assays to commercial products in the area of oral diagnostics have increased recently, as witnessed by the appearance of several new oral-based diagnostic products in the marketplace. Collaborative academic, government, and industry relationships in this arena are also forming, all of which will undoubtedly serve to rapidly advance the field. This volume brings together contributions from leaders in the areas of toxicology, pathology, oral biology, dental research, and clinical medicine. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit www.nyas.org/membership/main.asp for more information about becoming a member.
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Hinweis: Dieser Artikel kann nur an eine deutsche Lieferadresse ausgeliefert werden.
Produktdetails
- Produktdetails
- Verlag: Wiley
- Seitenzahl: 536
- Erscheinungstermin: 14. Mai 2007
- Englisch
- Abmessung: 229mm x 152mm x 29mm
- Gewicht: 767g
- ISBN-13: 9781573316613
- ISBN-10: 157331661X
- Artikelnr.: 22526711
- Verlag: Wiley
- Seitenzahl: 536
- Erscheinungstermin: 14. Mai 2007
- Englisch
- Abmessung: 229mm x 152mm x 29mm
- Gewicht: 767g
- ISBN-13: 9781573316613
- ISBN-10: 157331661X
- Artikelnr.: 22526711
Daniel Malamud and R. Sam Niedbala are the authors of Oral-Based Diagnostics, Volume 1098, published by Wiley.
Dedication to Irwin Mandel: Daniel Malamud. Introduction: Daniel Malamud and R. Sam Niedbala. Part I: Biochemistry/Physiology of Saliva: Implications for Diagnostics:. 1. Implications for Diagnostics in the Biochemistry and Physiology of Saliva: Arie V. Nieuw Amerongen
Antoon J. M. Ligtenberg
and Enno C. I. Veerman. 2. Point-of-Care Diagnostics Enter the Mouth: Lawrence A. Tabak. 3. Autoimmune Diseases and Sjögren's Syndrome: An Autoimmune Exocrinopathy: Philip C. Fox. 4. Salivary Proteome and Its Genetic Polymorphisms: Frank G. Oppenheim
Erdjan Salih
Walter L. Siqueira
Weimin Zhang
and Eva J. Helmerhorst. Part II: Drug and Small Molecule Detection in Saliva:. 5. Interpretation of Oral Fluid Tests for Drugs of Abuse: Edward J. Cone and Marilyn A. Huestis. 6. Methamphetamine Disposition in Oral Fluid
Plasma
and Urine: Marilyn A. Huestis and Edward J. Cone. 7. Salivary ¿-Amylase in Biobehavioral Research: Recent Developments and Applications: Douglas A. Granger
Katie T. Kivlighan
Mona El-Sheikh
Elena Gordis
and Laura R. Stroud. 8. The Use of Oral Fluid for Therapeutic Drug Management: Clinical and Forensic Toxicology: Loralie J. Langman. Part III: Meeting Unmet Needs in Diagnostics:. 9. Visualization and Other Emerging Technologies as Change Makers for Oral Cancer Prevention: Miriam P. Rosin
Catherine F. Poh
Martial Guillard
P. Michele Williams
Lewei Zhang
and Calum Macaulay. 10. Genomic Targets in Saliva: Bernhard G. Zimmermann
Noh Jin Park
and David T. Wong. 11. Saliva and the Clinical Pathology Laboratory: Michael A. Pesce and Steven L. Spitalnik. Part IV: Oral Samples/Oral Diseases:. 12. Oral Diseases: From Detection to Diagnostics: Antoon J. M. Ligtenberg
Johannes J. De Soet
Enno C. I. Veerman
and Arie V. Nieuw Amerongen. 13. A Novel Caries Risk Test: Paul C. Denny
Patricia A. Denny
Jona Takashima
Joyce Galligan
and Mahvash Navazesh. 14. Analysis of Gingival Crevicular Fluid as Applied to the Diagnosis of Oral and Systemic Diseases: Ira B. Lamster and Joseph K. Ahlo. 15. Oral Fluid-Based Biomarkers of Alveolar Bone Loss in Periodontitis: Janet S. Kinney
Christoph A. Ramseier
and William V. Giannobile. 16. Human Breath Odors and Their Use in Diagnosis: Chris L. Whittle
Steven Fakharzadeh
Jason Eades
and George Preti. Part V: Molecular and Protein Markers of Disease:. 17. Molecular and Protein Markers of Disease: Michael Glick. 18. Subclinical Cardiovascular Disease Markers Applicable to Studies of Oral Health: Multiethnic Study of Atherosclerosis: David R. Jacobs
Jr.
and Richard S. Crow. 19. Do Salivary Antibodies Reliably Reflect Both Mucosal and Systemic Immunity?: Per Brandtzaeg. 20. Oxytocin: Behavioral Associations and Potential as a Salivary Biomarker: C. Sue Carter
Hossein Pournajafi-Nazarloo
Kristin M. Kramer
Toni E. Ziegler
Rosemary White-Traut
Deborah Bello
and Dorie Schwertz. 21. Human Saliva Proteome Analysis: Shen Hu
Joseph A. Loo
and David T. Wong. Part VI: Horizons in Oral Diagnostics:. 22. Genomics and Proteomics: The Potential Role of Oral Diagnostics: Hans J. Tanke. 23. SPR Imaging-Based Salivary Diagnostics System for the Detection of Small Molecule Analytes: Elain Fu
Timothy Chinowsky
Kjell Nelson
Kyle Johnston
Thayne Edwards
Kristen Helton
Michael Grow
John W. Miller
and Paul Yager. 24. Saliva-Based Diagnostics Using 16S rRNA Microarrays and Microfluidics: E. Michelle Starke
James C. Smoot
Jer-Horng Wu
Wen-Tso Liu
Darrell Chandler
and David A. Stahl. 25. Integrated Microfluidic Platform for Oral Diagnostics: Amy E. Herr
Anson V. Hatch
William V. Giannobile
Daniel J. Throckmorton
Huu M. Tran
James S. Brennan
and Anup K. Singh. 26. Development of a Microfluidic Device for Detection of Pathogens in Oral Samples Using Upconverting Phosphor Technology (UPT): William R. Abrams
Cheryl A. Barber
Kurt McCann
Gary Tong
Zongyuan Y. Chen
Michael G. Mauk
Jing Wang
Alex Volkov
Pete Bourdelle
Paul L. A. M. Corstjens
Michel Zuiderwijk
Keith Kardos
Shang Li
Hans J. Tanke
R. Sam Niedbala
Daniel Malamud
and Haim Bau. 27. Microsensor Arrays for Saliva Diagnostics: David R. Walt
Timothy M. Blicharz
Ryan B. Hayman
David M. Rissin
Michaela Bowden
Walter L. Siqueira
Eva J. Helmerhorst
Nerline Grand-Pierre
Frank G. Oppenheim
Jasvinder S. Bhatia
Frederic F. Little
and Jerome S. Brody. 28. Oral Fluid Nanosensor Test (OFNASET) with Advanced Electrochemical-Based Molecular Analysis Platform: Vincent Gau and David Wong. 29. Lab-on-a-Chip Methods for Point-of-Care Measurements of Salivary Biomarkers of Periodontitis: Nicolaos Christodoulides
Pierre N. Floriano
Craig S. Miller
Jeffrey L. Ebersole
Sanghamitra Mohanty
Priya Dharshan
Michael Griffin
Alexis Lennart
Karri L. Michael Ballard
Charles P. King
Jr.
M. Chris Langub
Richard J. Kryscio
Mark V. Thomas
and John T. McDevitt. Part VII: Short Papers:. 30. A Microfluidic System for Saliva-Based Detection of Infectious Diseases: Zongyuan Chen
Michael G. Mauk
Jing Wang
William R. Abrams
Paul L. A. M. Corstjens
R. Samuel Niedbala
Daniel Malamud
and Haim H. Bau. 31. Rapid Assay Format for Multiplex Detection of Humoral Immune Responses to Infectious Disease Pathogens (HIV
HCV
and TB): Paul L. A. M. Corstjens
Zongyuang Chen
Michel Zuiderwijk
Haim H. Bau
William R. Abrams
Daniel Malamud
R. Sam Niedbala
and Hans J. Tanke. 32. Patterns of Salivary Estradiol and Progesterone across the Menstrual Cycle: Beatrice K. Gandara
Linda Leresche
and Lloyd Mancl. 33. Layered Peptide Arrays: A Diverse Technique for Antibody Screening of Clinical Samples: Gallya Gannot
Michael A. Tangrea
Rodrigo F. Chuaqui
John W. Gillespie
and Michael R. Emmert-Buck. 34. Whole Saliva Proteolysis: Wealth of Information for Diagnostic Exploitation: Eva J. Helmerhorst. 35. Saliva-Based HIV Testing among Secondary School Students in Tanzania using the OraQuick® Rapid HIV1/2 Antibody Assay: Carol Holm-Hansen
Balthazar Nyombi
and Mramba Nyindo. 36. Lab-on-a-Chip Technologies for Oral-Based Cancer Screening and Diagnostics: Capabilities
Issues
and Prospects: Michael G. Mauk
Barry L. Ziober
Zongyuan Chen
Jason A. Thompson
and Haim H. Bau. 37. Evaluation of UPlink-RSV: Prototype Rapid Antigen Test for Detection of Respiratory Syncytial Virus Infection: Vijaya K. Mokkapati
R. Sam Niedbala
Keith Kardos
Ronelito J. Perez
Ming Guo
Hans J. Tanke
and Paul L. A. M. Corstjens. 38. Immunoassay-Based Diagnostic Point-of-Care Technology for Oral Specimen: Sarvan Munjal
Peter Miethe
Lutz Netuschil
Friedhelm Struck
Kurt Maier
and Claus Bauermeister. 39. Evaluation of Immunoassay-Based MMP-8 Detection in Gingival Crevicular Fluid on a Point-of-Care Platform: S. K. Munjal
N. Prescher
F. Struck
T. Sorsa
K. Maier
and L. Netuschil. 40. Rapid Quantitative Chairside Test for Active MMP-8 in Gingival Crevicular Fluid: First Clinical Data: N. Prescher
K. Maier
S. K. Munjal
T. Sorsa
C.-D. Bauermeister
F. Struck
and L. Netuschil. 41. Salivary Biomarkers Associated with Alveolar Bone Loss: F. A. Scannapieco
Pby Ng
K. Hovey
E. Hausmann
A. Hutson
and J. Wactawski-Wende. 42. Salivary Protein/Peptide Profiling with SELDI-TOF-MS: Raymond Schipper
Arnoud Loof
Jolan De Groot
Lucien Harthoorn
Waander Van Heerde
and Eric Dransfield. 43. Acquired Enamel Pellicle and Its Potential Role in Oral Diagnostics: W. L. Siqueira
E. J. Helmerhorst
W. Zhang
E. Salih
and F. G. Oppenheim. 44. Gender-Specific Differences in Salivary Biomarker Responses to Acute Psychological Stress: Noriyasu Takai
Masaki Yamaguchi
Toshiaki Aragaki
Kenji Eto
Kenji Uchihashi
and Yasuo Nishikawa. Index of Contributors
Antoon J. M. Ligtenberg
and Enno C. I. Veerman. 2. Point-of-Care Diagnostics Enter the Mouth: Lawrence A. Tabak. 3. Autoimmune Diseases and Sjögren's Syndrome: An Autoimmune Exocrinopathy: Philip C. Fox. 4. Salivary Proteome and Its Genetic Polymorphisms: Frank G. Oppenheim
Erdjan Salih
Walter L. Siqueira
Weimin Zhang
and Eva J. Helmerhorst. Part II: Drug and Small Molecule Detection in Saliva:. 5. Interpretation of Oral Fluid Tests for Drugs of Abuse: Edward J. Cone and Marilyn A. Huestis. 6. Methamphetamine Disposition in Oral Fluid
Plasma
and Urine: Marilyn A. Huestis and Edward J. Cone. 7. Salivary ¿-Amylase in Biobehavioral Research: Recent Developments and Applications: Douglas A. Granger
Katie T. Kivlighan
Mona El-Sheikh
Elena Gordis
and Laura R. Stroud. 8. The Use of Oral Fluid for Therapeutic Drug Management: Clinical and Forensic Toxicology: Loralie J. Langman. Part III: Meeting Unmet Needs in Diagnostics:. 9. Visualization and Other Emerging Technologies as Change Makers for Oral Cancer Prevention: Miriam P. Rosin
Catherine F. Poh
Martial Guillard
P. Michele Williams
Lewei Zhang
and Calum Macaulay. 10. Genomic Targets in Saliva: Bernhard G. Zimmermann
Noh Jin Park
and David T. Wong. 11. Saliva and the Clinical Pathology Laboratory: Michael A. Pesce and Steven L. Spitalnik. Part IV: Oral Samples/Oral Diseases:. 12. Oral Diseases: From Detection to Diagnostics: Antoon J. M. Ligtenberg
Johannes J. De Soet
Enno C. I. Veerman
and Arie V. Nieuw Amerongen. 13. A Novel Caries Risk Test: Paul C. Denny
Patricia A. Denny
Jona Takashima
Joyce Galligan
and Mahvash Navazesh. 14. Analysis of Gingival Crevicular Fluid as Applied to the Diagnosis of Oral and Systemic Diseases: Ira B. Lamster and Joseph K. Ahlo. 15. Oral Fluid-Based Biomarkers of Alveolar Bone Loss in Periodontitis: Janet S. Kinney
Christoph A. Ramseier
and William V. Giannobile. 16. Human Breath Odors and Their Use in Diagnosis: Chris L. Whittle
Steven Fakharzadeh
Jason Eades
and George Preti. Part V: Molecular and Protein Markers of Disease:. 17. Molecular and Protein Markers of Disease: Michael Glick. 18. Subclinical Cardiovascular Disease Markers Applicable to Studies of Oral Health: Multiethnic Study of Atherosclerosis: David R. Jacobs
Jr.
and Richard S. Crow. 19. Do Salivary Antibodies Reliably Reflect Both Mucosal and Systemic Immunity?: Per Brandtzaeg. 20. Oxytocin: Behavioral Associations and Potential as a Salivary Biomarker: C. Sue Carter
Hossein Pournajafi-Nazarloo
Kristin M. Kramer
Toni E. Ziegler
Rosemary White-Traut
Deborah Bello
and Dorie Schwertz. 21. Human Saliva Proteome Analysis: Shen Hu
Joseph A. Loo
and David T. Wong. Part VI: Horizons in Oral Diagnostics:. 22. Genomics and Proteomics: The Potential Role of Oral Diagnostics: Hans J. Tanke. 23. SPR Imaging-Based Salivary Diagnostics System for the Detection of Small Molecule Analytes: Elain Fu
Timothy Chinowsky
Kjell Nelson
Kyle Johnston
Thayne Edwards
Kristen Helton
Michael Grow
John W. Miller
and Paul Yager. 24. Saliva-Based Diagnostics Using 16S rRNA Microarrays and Microfluidics: E. Michelle Starke
James C. Smoot
Jer-Horng Wu
Wen-Tso Liu
Darrell Chandler
and David A. Stahl. 25. Integrated Microfluidic Platform for Oral Diagnostics: Amy E. Herr
Anson V. Hatch
William V. Giannobile
Daniel J. Throckmorton
Huu M. Tran
James S. Brennan
and Anup K. Singh. 26. Development of a Microfluidic Device for Detection of Pathogens in Oral Samples Using Upconverting Phosphor Technology (UPT): William R. Abrams
Cheryl A. Barber
Kurt McCann
Gary Tong
Zongyuan Y. Chen
Michael G. Mauk
Jing Wang
Alex Volkov
Pete Bourdelle
Paul L. A. M. Corstjens
Michel Zuiderwijk
Keith Kardos
Shang Li
Hans J. Tanke
R. Sam Niedbala
Daniel Malamud
and Haim Bau. 27. Microsensor Arrays for Saliva Diagnostics: David R. Walt
Timothy M. Blicharz
Ryan B. Hayman
David M. Rissin
Michaela Bowden
Walter L. Siqueira
Eva J. Helmerhorst
Nerline Grand-Pierre
Frank G. Oppenheim
Jasvinder S. Bhatia
Frederic F. Little
and Jerome S. Brody. 28. Oral Fluid Nanosensor Test (OFNASET) with Advanced Electrochemical-Based Molecular Analysis Platform: Vincent Gau and David Wong. 29. Lab-on-a-Chip Methods for Point-of-Care Measurements of Salivary Biomarkers of Periodontitis: Nicolaos Christodoulides
Pierre N. Floriano
Craig S. Miller
Jeffrey L. Ebersole
Sanghamitra Mohanty
Priya Dharshan
Michael Griffin
Alexis Lennart
Karri L. Michael Ballard
Charles P. King
Jr.
M. Chris Langub
Richard J. Kryscio
Mark V. Thomas
and John T. McDevitt. Part VII: Short Papers:. 30. A Microfluidic System for Saliva-Based Detection of Infectious Diseases: Zongyuan Chen
Michael G. Mauk
Jing Wang
William R. Abrams
Paul L. A. M. Corstjens
R. Samuel Niedbala
Daniel Malamud
and Haim H. Bau. 31. Rapid Assay Format for Multiplex Detection of Humoral Immune Responses to Infectious Disease Pathogens (HIV
HCV
and TB): Paul L. A. M. Corstjens
Zongyuang Chen
Michel Zuiderwijk
Haim H. Bau
William R. Abrams
Daniel Malamud
R. Sam Niedbala
and Hans J. Tanke. 32. Patterns of Salivary Estradiol and Progesterone across the Menstrual Cycle: Beatrice K. Gandara
Linda Leresche
and Lloyd Mancl. 33. Layered Peptide Arrays: A Diverse Technique for Antibody Screening of Clinical Samples: Gallya Gannot
Michael A. Tangrea
Rodrigo F. Chuaqui
John W. Gillespie
and Michael R. Emmert-Buck. 34. Whole Saliva Proteolysis: Wealth of Information for Diagnostic Exploitation: Eva J. Helmerhorst. 35. Saliva-Based HIV Testing among Secondary School Students in Tanzania using the OraQuick® Rapid HIV1/2 Antibody Assay: Carol Holm-Hansen
Balthazar Nyombi
and Mramba Nyindo. 36. Lab-on-a-Chip Technologies for Oral-Based Cancer Screening and Diagnostics: Capabilities
Issues
and Prospects: Michael G. Mauk
Barry L. Ziober
Zongyuan Chen
Jason A. Thompson
and Haim H. Bau. 37. Evaluation of UPlink-RSV: Prototype Rapid Antigen Test for Detection of Respiratory Syncytial Virus Infection: Vijaya K. Mokkapati
R. Sam Niedbala
Keith Kardos
Ronelito J. Perez
Ming Guo
Hans J. Tanke
and Paul L. A. M. Corstjens. 38. Immunoassay-Based Diagnostic Point-of-Care Technology for Oral Specimen: Sarvan Munjal
Peter Miethe
Lutz Netuschil
Friedhelm Struck
Kurt Maier
and Claus Bauermeister. 39. Evaluation of Immunoassay-Based MMP-8 Detection in Gingival Crevicular Fluid on a Point-of-Care Platform: S. K. Munjal
N. Prescher
F. Struck
T. Sorsa
K. Maier
and L. Netuschil. 40. Rapid Quantitative Chairside Test for Active MMP-8 in Gingival Crevicular Fluid: First Clinical Data: N. Prescher
K. Maier
S. K. Munjal
T. Sorsa
C.-D. Bauermeister
F. Struck
and L. Netuschil. 41. Salivary Biomarkers Associated with Alveolar Bone Loss: F. A. Scannapieco
Pby Ng
K. Hovey
E. Hausmann
A. Hutson
and J. Wactawski-Wende. 42. Salivary Protein/Peptide Profiling with SELDI-TOF-MS: Raymond Schipper
Arnoud Loof
Jolan De Groot
Lucien Harthoorn
Waander Van Heerde
and Eric Dransfield. 43. Acquired Enamel Pellicle and Its Potential Role in Oral Diagnostics: W. L. Siqueira
E. J. Helmerhorst
W. Zhang
E. Salih
and F. G. Oppenheim. 44. Gender-Specific Differences in Salivary Biomarker Responses to Acute Psychological Stress: Noriyasu Takai
Masaki Yamaguchi
Toshiaki Aragaki
Kenji Eto
Kenji Uchihashi
and Yasuo Nishikawa. Index of Contributors
Dedication to Irwin Mandel: Daniel Malamud. Introduction: Daniel Malamud and R. Sam Niedbala. Part I: Biochemistry/Physiology of Saliva: Implications for Diagnostics:. 1. Implications for Diagnostics in the Biochemistry and Physiology of Saliva: Arie V. Nieuw Amerongen
Antoon J. M. Ligtenberg
and Enno C. I. Veerman. 2. Point-of-Care Diagnostics Enter the Mouth: Lawrence A. Tabak. 3. Autoimmune Diseases and Sjögren's Syndrome: An Autoimmune Exocrinopathy: Philip C. Fox. 4. Salivary Proteome and Its Genetic Polymorphisms: Frank G. Oppenheim
Erdjan Salih
Walter L. Siqueira
Weimin Zhang
and Eva J. Helmerhorst. Part II: Drug and Small Molecule Detection in Saliva:. 5. Interpretation of Oral Fluid Tests for Drugs of Abuse: Edward J. Cone and Marilyn A. Huestis. 6. Methamphetamine Disposition in Oral Fluid
Plasma
and Urine: Marilyn A. Huestis and Edward J. Cone. 7. Salivary ¿-Amylase in Biobehavioral Research: Recent Developments and Applications: Douglas A. Granger
Katie T. Kivlighan
Mona El-Sheikh
Elena Gordis
and Laura R. Stroud. 8. The Use of Oral Fluid for Therapeutic Drug Management: Clinical and Forensic Toxicology: Loralie J. Langman. Part III: Meeting Unmet Needs in Diagnostics:. 9. Visualization and Other Emerging Technologies as Change Makers for Oral Cancer Prevention: Miriam P. Rosin
Catherine F. Poh
Martial Guillard
P. Michele Williams
Lewei Zhang
and Calum Macaulay. 10. Genomic Targets in Saliva: Bernhard G. Zimmermann
Noh Jin Park
and David T. Wong. 11. Saliva and the Clinical Pathology Laboratory: Michael A. Pesce and Steven L. Spitalnik. Part IV: Oral Samples/Oral Diseases:. 12. Oral Diseases: From Detection to Diagnostics: Antoon J. M. Ligtenberg
Johannes J. De Soet
Enno C. I. Veerman
and Arie V. Nieuw Amerongen. 13. A Novel Caries Risk Test: Paul C. Denny
Patricia A. Denny
Jona Takashima
Joyce Galligan
and Mahvash Navazesh. 14. Analysis of Gingival Crevicular Fluid as Applied to the Diagnosis of Oral and Systemic Diseases: Ira B. Lamster and Joseph K. Ahlo. 15. Oral Fluid-Based Biomarkers of Alveolar Bone Loss in Periodontitis: Janet S. Kinney
Christoph A. Ramseier
and William V. Giannobile. 16. Human Breath Odors and Their Use in Diagnosis: Chris L. Whittle
Steven Fakharzadeh
Jason Eades
and George Preti. Part V: Molecular and Protein Markers of Disease:. 17. Molecular and Protein Markers of Disease: Michael Glick. 18. Subclinical Cardiovascular Disease Markers Applicable to Studies of Oral Health: Multiethnic Study of Atherosclerosis: David R. Jacobs
Jr.
and Richard S. Crow. 19. Do Salivary Antibodies Reliably Reflect Both Mucosal and Systemic Immunity?: Per Brandtzaeg. 20. Oxytocin: Behavioral Associations and Potential as a Salivary Biomarker: C. Sue Carter
Hossein Pournajafi-Nazarloo
Kristin M. Kramer
Toni E. Ziegler
Rosemary White-Traut
Deborah Bello
and Dorie Schwertz. 21. Human Saliva Proteome Analysis: Shen Hu
Joseph A. Loo
and David T. Wong. Part VI: Horizons in Oral Diagnostics:. 22. Genomics and Proteomics: The Potential Role of Oral Diagnostics: Hans J. Tanke. 23. SPR Imaging-Based Salivary Diagnostics System for the Detection of Small Molecule Analytes: Elain Fu
Timothy Chinowsky
Kjell Nelson
Kyle Johnston
Thayne Edwards
Kristen Helton
Michael Grow
John W. Miller
and Paul Yager. 24. Saliva-Based Diagnostics Using 16S rRNA Microarrays and Microfluidics: E. Michelle Starke
James C. Smoot
Jer-Horng Wu
Wen-Tso Liu
Darrell Chandler
and David A. Stahl. 25. Integrated Microfluidic Platform for Oral Diagnostics: Amy E. Herr
Anson V. Hatch
William V. Giannobile
Daniel J. Throckmorton
Huu M. Tran
James S. Brennan
and Anup K. Singh. 26. Development of a Microfluidic Device for Detection of Pathogens in Oral Samples Using Upconverting Phosphor Technology (UPT): William R. Abrams
Cheryl A. Barber
Kurt McCann
Gary Tong
Zongyuan Y. Chen
Michael G. Mauk
Jing Wang
Alex Volkov
Pete Bourdelle
Paul L. A. M. Corstjens
Michel Zuiderwijk
Keith Kardos
Shang Li
Hans J. Tanke
R. Sam Niedbala
Daniel Malamud
and Haim Bau. 27. Microsensor Arrays for Saliva Diagnostics: David R. Walt
Timothy M. Blicharz
Ryan B. Hayman
David M. Rissin
Michaela Bowden
Walter L. Siqueira
Eva J. Helmerhorst
Nerline Grand-Pierre
Frank G. Oppenheim
Jasvinder S. Bhatia
Frederic F. Little
and Jerome S. Brody. 28. Oral Fluid Nanosensor Test (OFNASET) with Advanced Electrochemical-Based Molecular Analysis Platform: Vincent Gau and David Wong. 29. Lab-on-a-Chip Methods for Point-of-Care Measurements of Salivary Biomarkers of Periodontitis: Nicolaos Christodoulides
Pierre N. Floriano
Craig S. Miller
Jeffrey L. Ebersole
Sanghamitra Mohanty
Priya Dharshan
Michael Griffin
Alexis Lennart
Karri L. Michael Ballard
Charles P. King
Jr.
M. Chris Langub
Richard J. Kryscio
Mark V. Thomas
and John T. McDevitt. Part VII: Short Papers:. 30. A Microfluidic System for Saliva-Based Detection of Infectious Diseases: Zongyuan Chen
Michael G. Mauk
Jing Wang
William R. Abrams
Paul L. A. M. Corstjens
R. Samuel Niedbala
Daniel Malamud
and Haim H. Bau. 31. Rapid Assay Format for Multiplex Detection of Humoral Immune Responses to Infectious Disease Pathogens (HIV
HCV
and TB): Paul L. A. M. Corstjens
Zongyuang Chen
Michel Zuiderwijk
Haim H. Bau
William R. Abrams
Daniel Malamud
R. Sam Niedbala
and Hans J. Tanke. 32. Patterns of Salivary Estradiol and Progesterone across the Menstrual Cycle: Beatrice K. Gandara
Linda Leresche
and Lloyd Mancl. 33. Layered Peptide Arrays: A Diverse Technique for Antibody Screening of Clinical Samples: Gallya Gannot
Michael A. Tangrea
Rodrigo F. Chuaqui
John W. Gillespie
and Michael R. Emmert-Buck. 34. Whole Saliva Proteolysis: Wealth of Information for Diagnostic Exploitation: Eva J. Helmerhorst. 35. Saliva-Based HIV Testing among Secondary School Students in Tanzania using the OraQuick® Rapid HIV1/2 Antibody Assay: Carol Holm-Hansen
Balthazar Nyombi
and Mramba Nyindo. 36. Lab-on-a-Chip Technologies for Oral-Based Cancer Screening and Diagnostics: Capabilities
Issues
and Prospects: Michael G. Mauk
Barry L. Ziober
Zongyuan Chen
Jason A. Thompson
and Haim H. Bau. 37. Evaluation of UPlink-RSV: Prototype Rapid Antigen Test for Detection of Respiratory Syncytial Virus Infection: Vijaya K. Mokkapati
R. Sam Niedbala
Keith Kardos
Ronelito J. Perez
Ming Guo
Hans J. Tanke
and Paul L. A. M. Corstjens. 38. Immunoassay-Based Diagnostic Point-of-Care Technology for Oral Specimen: Sarvan Munjal
Peter Miethe
Lutz Netuschil
Friedhelm Struck
Kurt Maier
and Claus Bauermeister. 39. Evaluation of Immunoassay-Based MMP-8 Detection in Gingival Crevicular Fluid on a Point-of-Care Platform: S. K. Munjal
N. Prescher
F. Struck
T. Sorsa
K. Maier
and L. Netuschil. 40. Rapid Quantitative Chairside Test for Active MMP-8 in Gingival Crevicular Fluid: First Clinical Data: N. Prescher
K. Maier
S. K. Munjal
T. Sorsa
C.-D. Bauermeister
F. Struck
and L. Netuschil. 41. Salivary Biomarkers Associated with Alveolar Bone Loss: F. A. Scannapieco
Pby Ng
K. Hovey
E. Hausmann
A. Hutson
and J. Wactawski-Wende. 42. Salivary Protein/Peptide Profiling with SELDI-TOF-MS: Raymond Schipper
Arnoud Loof
Jolan De Groot
Lucien Harthoorn
Waander Van Heerde
and Eric Dransfield. 43. Acquired Enamel Pellicle and Its Potential Role in Oral Diagnostics: W. L. Siqueira
E. J. Helmerhorst
W. Zhang
E. Salih
and F. G. Oppenheim. 44. Gender-Specific Differences in Salivary Biomarker Responses to Acute Psychological Stress: Noriyasu Takai
Masaki Yamaguchi
Toshiaki Aragaki
Kenji Eto
Kenji Uchihashi
and Yasuo Nishikawa. Index of Contributors
Antoon J. M. Ligtenberg
and Enno C. I. Veerman. 2. Point-of-Care Diagnostics Enter the Mouth: Lawrence A. Tabak. 3. Autoimmune Diseases and Sjögren's Syndrome: An Autoimmune Exocrinopathy: Philip C. Fox. 4. Salivary Proteome and Its Genetic Polymorphisms: Frank G. Oppenheim
Erdjan Salih
Walter L. Siqueira
Weimin Zhang
and Eva J. Helmerhorst. Part II: Drug and Small Molecule Detection in Saliva:. 5. Interpretation of Oral Fluid Tests for Drugs of Abuse: Edward J. Cone and Marilyn A. Huestis. 6. Methamphetamine Disposition in Oral Fluid
Plasma
and Urine: Marilyn A. Huestis and Edward J. Cone. 7. Salivary ¿-Amylase in Biobehavioral Research: Recent Developments and Applications: Douglas A. Granger
Katie T. Kivlighan
Mona El-Sheikh
Elena Gordis
and Laura R. Stroud. 8. The Use of Oral Fluid for Therapeutic Drug Management: Clinical and Forensic Toxicology: Loralie J. Langman. Part III: Meeting Unmet Needs in Diagnostics:. 9. Visualization and Other Emerging Technologies as Change Makers for Oral Cancer Prevention: Miriam P. Rosin
Catherine F. Poh
Martial Guillard
P. Michele Williams
Lewei Zhang
and Calum Macaulay. 10. Genomic Targets in Saliva: Bernhard G. Zimmermann
Noh Jin Park
and David T. Wong. 11. Saliva and the Clinical Pathology Laboratory: Michael A. Pesce and Steven L. Spitalnik. Part IV: Oral Samples/Oral Diseases:. 12. Oral Diseases: From Detection to Diagnostics: Antoon J. M. Ligtenberg
Johannes J. De Soet
Enno C. I. Veerman
and Arie V. Nieuw Amerongen. 13. A Novel Caries Risk Test: Paul C. Denny
Patricia A. Denny
Jona Takashima
Joyce Galligan
and Mahvash Navazesh. 14. Analysis of Gingival Crevicular Fluid as Applied to the Diagnosis of Oral and Systemic Diseases: Ira B. Lamster and Joseph K. Ahlo. 15. Oral Fluid-Based Biomarkers of Alveolar Bone Loss in Periodontitis: Janet S. Kinney
Christoph A. Ramseier
and William V. Giannobile. 16. Human Breath Odors and Their Use in Diagnosis: Chris L. Whittle
Steven Fakharzadeh
Jason Eades
and George Preti. Part V: Molecular and Protein Markers of Disease:. 17. Molecular and Protein Markers of Disease: Michael Glick. 18. Subclinical Cardiovascular Disease Markers Applicable to Studies of Oral Health: Multiethnic Study of Atherosclerosis: David R. Jacobs
Jr.
and Richard S. Crow. 19. Do Salivary Antibodies Reliably Reflect Both Mucosal and Systemic Immunity?: Per Brandtzaeg. 20. Oxytocin: Behavioral Associations and Potential as a Salivary Biomarker: C. Sue Carter
Hossein Pournajafi-Nazarloo
Kristin M. Kramer
Toni E. Ziegler
Rosemary White-Traut
Deborah Bello
and Dorie Schwertz. 21. Human Saliva Proteome Analysis: Shen Hu
Joseph A. Loo
and David T. Wong. Part VI: Horizons in Oral Diagnostics:. 22. Genomics and Proteomics: The Potential Role of Oral Diagnostics: Hans J. Tanke. 23. SPR Imaging-Based Salivary Diagnostics System for the Detection of Small Molecule Analytes: Elain Fu
Timothy Chinowsky
Kjell Nelson
Kyle Johnston
Thayne Edwards
Kristen Helton
Michael Grow
John W. Miller
and Paul Yager. 24. Saliva-Based Diagnostics Using 16S rRNA Microarrays and Microfluidics: E. Michelle Starke
James C. Smoot
Jer-Horng Wu
Wen-Tso Liu
Darrell Chandler
and David A. Stahl. 25. Integrated Microfluidic Platform for Oral Diagnostics: Amy E. Herr
Anson V. Hatch
William V. Giannobile
Daniel J. Throckmorton
Huu M. Tran
James S. Brennan
and Anup K. Singh. 26. Development of a Microfluidic Device for Detection of Pathogens in Oral Samples Using Upconverting Phosphor Technology (UPT): William R. Abrams
Cheryl A. Barber
Kurt McCann
Gary Tong
Zongyuan Y. Chen
Michael G. Mauk
Jing Wang
Alex Volkov
Pete Bourdelle
Paul L. A. M. Corstjens
Michel Zuiderwijk
Keith Kardos
Shang Li
Hans J. Tanke
R. Sam Niedbala
Daniel Malamud
and Haim Bau. 27. Microsensor Arrays for Saliva Diagnostics: David R. Walt
Timothy M. Blicharz
Ryan B. Hayman
David M. Rissin
Michaela Bowden
Walter L. Siqueira
Eva J. Helmerhorst
Nerline Grand-Pierre
Frank G. Oppenheim
Jasvinder S. Bhatia
Frederic F. Little
and Jerome S. Brody. 28. Oral Fluid Nanosensor Test (OFNASET) with Advanced Electrochemical-Based Molecular Analysis Platform: Vincent Gau and David Wong. 29. Lab-on-a-Chip Methods for Point-of-Care Measurements of Salivary Biomarkers of Periodontitis: Nicolaos Christodoulides
Pierre N. Floriano
Craig S. Miller
Jeffrey L. Ebersole
Sanghamitra Mohanty
Priya Dharshan
Michael Griffin
Alexis Lennart
Karri L. Michael Ballard
Charles P. King
Jr.
M. Chris Langub
Richard J. Kryscio
Mark V. Thomas
and John T. McDevitt. Part VII: Short Papers:. 30. A Microfluidic System for Saliva-Based Detection of Infectious Diseases: Zongyuan Chen
Michael G. Mauk
Jing Wang
William R. Abrams
Paul L. A. M. Corstjens
R. Samuel Niedbala
Daniel Malamud
and Haim H. Bau. 31. Rapid Assay Format for Multiplex Detection of Humoral Immune Responses to Infectious Disease Pathogens (HIV
HCV
and TB): Paul L. A. M. Corstjens
Zongyuang Chen
Michel Zuiderwijk
Haim H. Bau
William R. Abrams
Daniel Malamud
R. Sam Niedbala
and Hans J. Tanke. 32. Patterns of Salivary Estradiol and Progesterone across the Menstrual Cycle: Beatrice K. Gandara
Linda Leresche
and Lloyd Mancl. 33. Layered Peptide Arrays: A Diverse Technique for Antibody Screening of Clinical Samples: Gallya Gannot
Michael A. Tangrea
Rodrigo F. Chuaqui
John W. Gillespie
and Michael R. Emmert-Buck. 34. Whole Saliva Proteolysis: Wealth of Information for Diagnostic Exploitation: Eva J. Helmerhorst. 35. Saliva-Based HIV Testing among Secondary School Students in Tanzania using the OraQuick® Rapid HIV1/2 Antibody Assay: Carol Holm-Hansen
Balthazar Nyombi
and Mramba Nyindo. 36. Lab-on-a-Chip Technologies for Oral-Based Cancer Screening and Diagnostics: Capabilities
Issues
and Prospects: Michael G. Mauk
Barry L. Ziober
Zongyuan Chen
Jason A. Thompson
and Haim H. Bau. 37. Evaluation of UPlink-RSV: Prototype Rapid Antigen Test for Detection of Respiratory Syncytial Virus Infection: Vijaya K. Mokkapati
R. Sam Niedbala
Keith Kardos
Ronelito J. Perez
Ming Guo
Hans J. Tanke
and Paul L. A. M. Corstjens. 38. Immunoassay-Based Diagnostic Point-of-Care Technology for Oral Specimen: Sarvan Munjal
Peter Miethe
Lutz Netuschil
Friedhelm Struck
Kurt Maier
and Claus Bauermeister. 39. Evaluation of Immunoassay-Based MMP-8 Detection in Gingival Crevicular Fluid on a Point-of-Care Platform: S. K. Munjal
N. Prescher
F. Struck
T. Sorsa
K. Maier
and L. Netuschil. 40. Rapid Quantitative Chairside Test for Active MMP-8 in Gingival Crevicular Fluid: First Clinical Data: N. Prescher
K. Maier
S. K. Munjal
T. Sorsa
C.-D. Bauermeister
F. Struck
and L. Netuschil. 41. Salivary Biomarkers Associated with Alveolar Bone Loss: F. A. Scannapieco
Pby Ng
K. Hovey
E. Hausmann
A. Hutson
and J. Wactawski-Wende. 42. Salivary Protein/Peptide Profiling with SELDI-TOF-MS: Raymond Schipper
Arnoud Loof
Jolan De Groot
Lucien Harthoorn
Waander Van Heerde
and Eric Dransfield. 43. Acquired Enamel Pellicle and Its Potential Role in Oral Diagnostics: W. L. Siqueira
E. J. Helmerhorst
W. Zhang
E. Salih
and F. G. Oppenheim. 44. Gender-Specific Differences in Salivary Biomarker Responses to Acute Psychological Stress: Noriyasu Takai
Masaki Yamaguchi
Toshiaki Aragaki
Kenji Eto
Kenji Uchihashi
and Yasuo Nishikawa. Index of Contributors