Ibuprofen with new derivatives
Containing 4-oxothiazolidin (amino moiety) with expected biological action
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In this book, 5-membered-ring of heterocyclic compounds have been prepared by reaction of Schiff base derivatives of Ibuprofen with mercapto-acetic acid . The study aimed to synthesize derivatives of ibuprofen with more potency and to decrease the drug's potential side effects, a new series of 4-thiazolidinone derivatives of ibuprofen was synthesized VI a-e . The characterization of the titled compounds they were identified on the basis of their spectral FTIR, 1HNMR technique , and by measuring the physical properties.
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