Cardiovascular And Neuromodulatory Effects Of Purine P1 Agonists - Thabet, Romany;Mohammed Al-Sharari, Duaa;Alhadi N. Alanazi, Modhi
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The present work investigates the effect of rats pretreatment with the purinergic agonists ADO, 2-CADO, CPA and CPCA on the forebrain levels of the neurotransmitters glutamate and GABA in rats after PTZ challenge. In a trial to correlates cardiovascular effects with the neuromodulatory effects of the aforementioned agonists , the CVS effects of these agonists in addition to determination of their TD50 before and after PTZ- induced seizures were also investigated.

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Produktbeschreibung
The present work investigates the effect of rats pretreatment with the purinergic agonists ADO, 2-CADO, CPA and CPCA on the forebrain levels of the neurotransmitters glutamate and GABA in rats after PTZ challenge. In a trial to correlates cardiovascular effects with the neuromodulatory effects of the aforementioned agonists , the CVS effects of these agonists in addition to determination of their TD50 before and after PTZ- induced seizures were also investigated.
Autorenporträt
Dr.Romany Helmy Thabet, Assistant Professor of pharmacology, Faculty of Medicine, Northern Borders University, Saudi Arabia. So interested in immunopharmacology and pharmacogenomics research. My Latest Publications is titled''Genetic variants in 6-mercaptopurine pathway as potential factors of hematological toxicity in acute lymphoblastic leukemia