Many different materials have been advocated for use as retrograde filling materials, and each has specific advantages and disadvan-tages. However from the biological perspective of regeneration of periradicular tissues, MTA remains to be the material of choice and is considered the gold standard for all the future root end filling materials.Though retrograde filling materials not much recommended in earlier days, plays a significant role in the success of endodontic surgery. The endodontic surgeon should consider using materials, which have been clinically and biologically evaluated and which give evidence of long-term success. The introduction of ultrasonic tips and micro surgical instruments helps the operator to place the retrograde filling materials with much desired accuracy and precision.
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