This work examines young women s decision-making experiences related to Human Papillomavirus (HPV) vaccination. Using a narrative research approach, five young women were asked to share their stories of how they came to be or not be vaccinated. Participant narratives reveal a number of themes that capture the diversity of young women s experiences and point to the complex ways in which individuals often negotiate decisions regarding vaccination. In her work, the author takes a critical stance on the topic of HPV vaccine decision-making in order to illuminate how young women s decisions are embedded within broader social and discursive contexts. This critical approach to understanding participant narratives is informed by a strong sensitivity to conceptual frames of medicalization, healthism, and neo-medicalization and dominant discourses related to health risk and individual responsibility.