This book has provided the reader with an introduction to the instrumentation and column technology used in CEC and nano-LC as well as an overview of the various separation principles of CEC. Furthermore, it has summarized and discussed the advances made in the various kinds of polymer- based monolithic columns including those bearing affinity ligands on their surface The overall investigation described in this book has contributed to enlarging the scope of CEC and nano- LC by demonstrating their capabilities in areas that were not exploited previously. Also, the novel stationary phases developed within the framework of this investigation will not only facilitate the solution of many important analytical separation problems in the life sciences, but will also contribute to new concepts that will open the way to increasing the utility of the technique in the future.