Preface 1. Fever - definition, usefulness, ubiquity 2. Thermoregulation - an outline 3. The nature of pyrogens, their origins and mode of release 4. The loci of action of endogenous mediators of fever 5. Beyond the loci of action of circulating pyrogens: mediators and mechanisms 6. The role of the cerebral cortex, the limbic system, peripheral nervous system and spinal cord, and induced changes in intracranial pressure 7. Antipyresis 8. Febrile convulsions in children and a possible role for vasopressin 9. A synthesis, predictions and speculation from my armchair Appendix 1: Anatomical considerations References Index.
Preface 1. Fever - definition, usefulness, ubiquity 2. Thermoregulation - an outline 3. The nature of pyrogens, their origins and mode of release 4. The loci of action of endogenous mediators of fever 5. Beyond the loci of action of circulating pyrogens: mediators and mechanisms 6. The role of the cerebral cortex, the limbic system, peripheral nervous system and spinal cord, and induced changes in intracranial pressure 7. Antipyresis 8. Febrile convulsions in children and a possible role for vasopressin 9. A synthesis, predictions and speculation from my armchair Appendix 1: Anatomical considerations References Index.
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