Simultaneous Analysis of Mebeverine Hydrochloride and Chlordiazepoxide
Spectrophotometric and Chromatographic Determination of Binary Mixture of Mebeverine Hydrochloride and Chlordiazepoxide in Coloverin® A Tablets
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Absorption spectrophotometry is one of the most powerful tools used for the quantitative analysis of any analyte. The relation between the concentration of the analyte and the amount of light absorbed is the basis of most analytical applications of molecular spectroscopy. This method of analysis is gaining importance due to simple, rapid, precise, cheap, highly accurate and less time consuming. Spectrophotometric multi-component analysis can be applied where the spectra of drugs overlaps. In such cases of overlapping spectra, the simultaneous equation can be framed to obtain the concentration ...
Absorption spectrophotometry is one of the most powerful tools used for the quantitative analysis of any analyte. The relation between the concentration of the analyte and the amount of light absorbed is the basis of most analytical applications of molecular spectroscopy. This method of analysis is gaining importance due to simple, rapid, precise, cheap, highly accurate and less time consuming. Spectrophotometric multi-component analysis can be applied where the spectra of drugs overlaps. In such cases of overlapping spectra, the simultaneous equation can be framed to obtain the concentration of each individual component; otherwise, multi-component analysis can be applied on any degree of spectral overlap provided that two or more spectra are not exactly similar. The aim of this work was to develop simple, sensitive, selective and precise spectrophotometric methods for simultaneous determination of MVH and CDZ in their pure powdered form and pharmaceutical formulation without prior separation steps via different manipulating pathways.
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