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Aging is accompanied by generation of free radical. Thus, the present study aimed to limit or inhibit free radical production. It is well known that antioxidants scavenge free radical production. Therefore, mixture of antioxidants was used in this study as an attempt to reduce the rate of formation of aging changes. And so, the importance of using natural products is derived. For this reason, most of the next researches centered on using natural medicine in many diseases.