Neuroendocrine Cells and Peptidergic Innervation in Human and Rat Prostrate

Neuroendocrine Cells and Peptidergic Innervation in Human and Rat Prostrate

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1 Introduction The prostate causes a signi?cant number of medical problems in the adult male, and the lower urinary tract symptoms are accepted as an unavoidable consequence of male aging. Most of these symptoms are mainly due to clinical benign prostatic hyperplasia (BPH), which is the most frequent benign tumor in the male, in- pendent of race or culture. On the other hand, cancer of the prostate shows an increasing incidence, being the second leading cause of death in men, after lung cancer. It has an etiology related to multiple factors: age, race, androgen dep- dence, chemical agents, die...