Postdural puncture headache (PPH) is the most common major complication following neuraxial anesthesia and this adverse event usually happens in obstetrics. Although the headache that may appear is often self-limiting, in most cases it is unpleasant or painful, and it can become incapacitating and associated with very serious complications. PPH is the most frequent complication associated with epidural analgesia. Its incidence has been decreasing over the years, mainly due, among many other factors, to greater experience of the anesthesiologist, the improvement of techniques and the use of small gauge and non-cutting tip needles. This book revises all the aspects about this subject, including all the treatments descrived up to now.