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A laser spallation technique, which was originally
developed to measure adhesion of thin films, was
adopted to determine the interfacial tensile
strength of cells and mineralized tissue to various
engineered substrates.
Several new experimental equipments, procedures, and
analyzing methods were successfully developed
considering the characteristics of biological
specimens. Also, new machinery of analysis that
enhances the calculation accuracy and efficiency was
developed, and as final calculation methods, both
FEA simulation and analytical method were adopted
and compared with each other.
Interfacial tensile strengths of living cells were
successfully measured, and so were its dependence on
different surface conditions, including polymer and
metal substrates and the presence or absence of
fibronectin treatment and serum.
The feasibility of the living cell isolating and
placing method using the laser spallation technique
was positively demonstrated suggesting the
possibility of the method to enhance existing
individual living cell manipulation techniques for
precise placement.
developed to measure adhesion of thin films, was
adopted to determine the interfacial tensile
strength of cells and mineralized tissue to various
engineered substrates.
Several new experimental equipments, procedures, and
analyzing methods were successfully developed
considering the characteristics of biological
specimens. Also, new machinery of analysis that
enhances the calculation accuracy and efficiency was
developed, and as final calculation methods, both
FEA simulation and analytical method were adopted
and compared with each other.
Interfacial tensile strengths of living cells were
successfully measured, and so were its dependence on
different surface conditions, including polymer and
metal substrates and the presence or absence of
fibronectin treatment and serum.
The feasibility of the living cell isolating and
placing method using the laser spallation technique
was positively demonstrated suggesting the
possibility of the method to enhance existing
individual living cell manipulation techniques for
precise placement.