This book Artificial intelligence in chemical engineering practice outlines human-assisted intelligent computing, process development and design, operation and control, optimization, safety, and reliability, provide some philosophy, and give some motivation for becoming familiar with this topic. Knowledge processing and information producing was studied. This simulation by expert systems coordinates all symbolic reasoning systems and numerical routines in an integrated intelligent system. In most aspects of industrial life, continual improvement is an important feature. Thus need to get the largest production from given raw materials, the greatest profit from a fixed investment, and so on.Optimization is a formal presentation of these ideas. The book concentrates on neural networks and applications to process analysis, control, optimization, and fault recognition and classification as well as neural-fuzzy models. This book illustrates the concept of modular modelling and distributive diagnosis in chemical engineering, and computer-aided process engineering. The book includes innovative methods and human-assisted intelligent computing, too.