The book deals with the very Important Indian Medicinal plants Andrographis paniculata and Sesbania grandiflora used for the Liver and Kidney biomedicine. The main objective of this work is to study the phytochemical analysis of two indian medicinal plants, Andrographis paniculata and Sesbania grandiflora Aqueous, Ethanol and Acetone extracts and its antimicrobial potential, Antioxidant effect, hepatorenal protective activity and anticancer activity.