Laurence Moran, Robert Horton, Gray Scrimgeour

Principles of Biochemistry

Pearson New International Edition

• Broschiertes Buch

Produktbeschreibung

Principles of Biochemistry provides a concise introduction to fundamental concepts of biochemistry, striking the right balance of rigor and detail between the encyclopedic volumes and the cursory overview texts available today. Widely praised for accuracy, currency, and clarity of exposition, the Fifth Edition offers a new student-friendly design, an enhanced visual program, new Application Boxes, contemporary research integrated throughout, and updated end-of-chapter problems. Features + Benefits

Unique focus on principles and underlying themes of biochemistry fosters understanding rather than simply relating facts. By first establishing a framework of key principles then reinforcing them with the careful use of illustrative examples, the Fifth Edition encourages and fosters true understanding of the relationship between structure and function, instead of memorization.

Balanced coverage of biomolecular structure/function, metabolism, and molecular biology provides instructors with thorough, consistent coverage of all the topics they cover in class.

Strong chemical focus, including mechanisms of reactions and attention to the physical chemistry of biomolecules, explains how and why reactions happen so students can understand more and memorize less.

Emphasis on oxidation-reduction reactions expands coverage of these important reactions and explains electron gain and loss in a simple and straightforward manner.

The Evolutionary approach to biochemistry explains the fundamental strategies of metabolic pathways from the perspective of how they evolved.

Authoritatively written by a collaborative team of experts, the text provides clear, lucid explanations and accurate science for all areas of biochemistry. (Ex. DNA replication.)

Chapters on amino acid, lipid, and nucleotide metabolism stress core concepts enable students to leave the course with a solid understanding of the key issues of metabolism without losing sight of the forest for the trees.

Excellent coverage of gene expression includes the structure of RNA polymerase, the structure of the ribosome, genome organization, repair mechanisms, regulation of transcription and translation, and the structure and evolution of aminoacyl tRNA synthetases.

Boxes focus on interesting science, commercial applications of biochemistry, and medical relevance:
Boxes on enzyme evolution, enzyme microheterogeneity, sources of electrons in redox reactions, and the origins of common names help stimulate student’s interest in the science of biochemistry.

Boxes on genetically modified foods and improving crop production illustrate some of the commercial applications of biochemistry.

Boxes on ABO blood groups, statins, and common painkillers illustrate principles described in the text using clinical examples.

(NOTE: Each chapter concludes with Summary, Problems, and Selected Reading.)

Part One: Introduction
1 Introduction to Biochemistry
2 Water

Part Two: Structure and Function
3 Amino Acids and the Primary Structures of Proteins
4 Proteins: Three-Dimensional Structure and Function
5 Properties of Enzymes
6 Mechanisms of Enzymes
7 Carbohydrates

8 Coenzymes and Vitamins
9 Lipids and Membranes

Part Three: Metabolism and Bioenergetics
10 Introduction to Metabolism
11 Glycolysis
12 Gluconeogenesis, The Pentose Phosphate Pathway, and Glycogen Metabolism
13 The Citric Acid Cycle
14 Electron Transport and ATP Synthesis
15 Photosynthesis
16 Lipid Metabolism
17 Amino Acid Metabolism
18 Nucleotide Metabolism

Part Four: Biological Information Flow
19 Nucleic Acids
20 DNA Replication, Repair, and Recombination
21 Transcription and RNA Processing
22 Protein Synthesis

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Produktdetails

• Verlag: Pearson Education Limited
• 5 ed
• Seitenzahl: 800
• Erscheinungstermin: 6. August 2013
• Englisch
• Abmessung: 279mm x 219mm x 35mm
• Gewicht: 1618g
• ISBN-13: 9781292021744
• ISBN-10: 1292021748
• Artikelnr.: 48550347

Autorenporträt

Laurence A. Moran After earning his Ph.D from Princeton University in 1974, Professor Moran spent four years at the Université dè Geneve in Switzerland. He has been a member of the Department of Biochemistry at the University of Toronto since 1978, specializing in molecular biology and molecular evolution. His research findings on heat-shock genes have been published in many scholarly journals. H. Robert Horton Dr. Horton, who received his Ph.D from the University of Missouri in 1962, is William Neal Reynolds Professor Emeritus and Alumni Distinguished Professor Emeritus in the Department of Biochemistry at North Carolina State University, where he served on the faculty for over 30 years. Most of Professor Horton’s research was in protein and enzyme mechanisms. K. Gray Scrimgeour Professor Scrimgeour received his doctorate from the University of Washington in 1961 and has been a faculty member at the University of Toronto since 1967. He is the author of The Chemistry and Control of Enzymatic Reactions (1977, Academic Press), and his work on enzymatic systems has been published in more than 50 professional journal articles during the past 40 years. From 1984—1992, he was editor of the journal Biochemistry and Cell Biology. Marc D. Perry After earning his Ph.D. from the University of Toronto in 1988, Dr. Perry trained at the University of Colorado, where he studied sex determination in the nematode C. elegans. In 1994 he returned to the University of Toronto as a faculty member in the department of Molecular and Medical Genetics. His research has focused on developmental genetics, meiosis and bioinformatics. In 2004 he joined the Heart & Stroke / Richard Lewar Centre of Excellence in Cardiovascular Research in the University of Toronto’s Faculty of Medicine.

Inhaltsangabe

(NOTE: Each chapter concludes with Summary, Problems, and Selected
Reading.)
Part One: Introduction
1 Introduction to Biochemistry
2 Water
Part Two: Structure and Function
3 Amino Acids and the Primary Structures of Proteins
4 Proteins: Three-Dimensional Structure and Function
5 Properties of Enzymes
6 Mechanisms of Enzymes
7 Carbohydrates
8 Coenzymes and Vitamins
9 Lipids and Membranes
Part Three: Metabolism and Bioenergetics 
10 Introduction to Metabolism
11 Glycolysis
12 Gluconeogenesis, The Pentose Phosphate Pathway, and Glycogen Metabolism
13 The Citric Acid Cycle
14 Electron Transport and ATP Synthesis
15 Photosynthesis
16 Lipid Metabolism
17 Amino Acid Metabolism
18 Nucleotide Metabolism
Part Four: Biological Information Flow
19 Nucleic Acids
20 DNA Replication, Repair, and Recombination
21 Transcription and RNA Processing
22 Protein Synthesis