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Some students were helping me with experiments that are mentioned here. From all of them I would like to thank Benjamin Waldmann and Marcel Lietz who were the first students and who I kept contact over the time. Also Monika Alter and Tobias Fister who convinced me to take one more group of students should be mentioned as they generated data that explained a lot. I asked friends to proof-read one part or the other of this work. Dr. Meike Römer, Dr. Katrin Kinkel, Dr. Cornelius Pompe, Torge Schiefelbein, Dr. Martin Meyer, I really thank you for the quick responses and the scientific input I got.