Leland H Hartwell, Leroy Hood, Michael L Goldberg, Ann E Reynolds, Lee M Silver

Genetics: From Genes to Genomes

• Broschiertes Buch

Produktbeschreibung

Genetics: From Genes to Genomes is a cutting-edge, introductory genetics text authored by an unparalleled author team, including Nobel Prize winner, Leland Hartwell. The 4th edition continues to build upon the integration of Mendelian and molecular principles, providing students with the links between the early understanding of genetics and the new molecular discoveries that have changed the way the field of genetics is viewed.

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Produktdetails

• Verlag: McGraw-Hill Education
• 4th edition
• Erscheinungstermin: 4. November 2010
• Englisch
• Abmessung: 282mm x 221mm x 30mm
• Gewicht: 1860g
• ISBN-13: 9780077471972
• ISBN-10: 0077471970
• Artikelnr.: 33371742

Autorenporträt

Dr. Leland Hartwell is President and Director of Seattles Fred Hutchinson CancerResearch Center and Professor of Genome Sciences at the University of Washington.Dr. Hartwells primary research contributions were in identifying genes that controlcell division in yeast, including those necessary for the division process as well asthose necessary for the fi delity of genome reproduction. Subsequently, many of thesesame genes have been found to control cell division in humans and oft en to be thesite of alteration in cancer cells.Dr. Hartwell is a member of the National Academy of Sciences and has receivedthe Albert Lasker Basic Medical Research Award, the Gairdner FoundationInternational Award, the Genetics Society Medal, and the 2001 Nobel Prize inPhysiology or Medicine.

Inhaltsangabe

1 Genetics: The Study of Biological Information PART I Basic Principles:
How Traits Are Transmitted 2 Mendel's Breakthrough: Patterns, Particles,
and Principles of Heredity 3 Extensions to Mendel: Complexities in Relating
Genotype to Phenotype 4 The Chromosome Theory of Inheritance 5 Linkage,
Recombination, and the Mapping of Genes on Chromosomes PART II What Genes
Are and What They Do 6 DNA: Structure, Replication, and Recombination 7
Anatomy and Function of a Gene: Dissection Through Mutation PART III
Analysis of Genetic Information
10 Genomes and Proteomes 11 Genome-Wide Variation and Trait Analysis PART
IV How Genes Travel on Chromosomes 12 The Eukaryotic Chromosome 13
Chromosomal Rearrangements and Changes in Chromosome Number Reshape
Eukaryotic Genomes 14 The Prokaryotic Chromosome: Genetic Analysis in
Bacteria PART V How Genes Are Regulated 15 Gene Regulation in Prokaryotes
16 Gene Regulation in Eukaryotes 17 Somatic Mutation and the Genetics of
Cancer 18 Using Genetics to Study Development PART VI Genetics Beyond the
Individual 19 Variation and Selection in Populations 20 Evolution at the
Molecular Level PART VIII Systems Biology 21 Systems Biology and the Future
of Medicine