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This book on AMA1 malaria vaccine candidate present some of the various brands of AMA1 attempted through various techniques in vaccinology, the shortcomings, challenges posed and problems encountered with these vaccines. This work searched for reasons behind these problems and chipped in vital facts related to the presently- only malaria vaccine which has crossed the difficult Phase III clinical trial for malaria vaccine, in relation to efforts to engage AMA1 in vaccinology.