Gracia-Sancho BSc, M. Josepa Salvadó

Gastrointestinal Tissue (eBook, ePUB)

Oxidative Stress and Dietary Antioxidants

• Format: ePub

Produktbeschreibung

Gastrointestinal Tissue: Oxidative Stress and Dietary Antioxidants brings together leading experts from world renowned institutions, combining the basic mechanisms of gastrointestinal diseases with information regarding new and alternative treatments.

The processes within the science of oxidative stress are described in concert with other processes, including apoptosis, cell signaling and receptor mediated responses, further recognizing that diseases are often multifactorial with oxidative stress as a component. By combining the critical molecular processes underlying free radical mediated pathologies and the role of dietary antioxidant molecules, a connection is made that helps advance therapies and the prevention of gastrointestinal pathological processes.

This important reference is well designed with two complementary sections. Section One, Oxidative Stress and Gastroenterology, covers the basic processes of oxidative stress from molecular biology to whole organs, the gastrointestinal anatomy and sources of oxidative stress and free radicals and their products in gastrointestinal diseases. Section Two, Antioxidants and Gastroenterology covers antioxidants in foods, including plants and components.

• Covers the science of oxidative stress in gastrointestinal tissue and associated conditions and scenarios
• Provides information on optimal levels for human consumption of antioxidants, suggested requirements per day, recommended dietary allowances and curative/preventive effects of dietary antioxidants
• Presents an easy to reference guide with two complementary sections that discuss the pathophysiology of gastrointestinal diseases in relation to oxidative stress and antioxidant therapies

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Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 394
• Erscheinungstermin: 10. Mai 2017
• Englisch
• ISBN-13: 9780128093009
• Artikelnr.: 48244327

Autorenporträt

Jordi Gracia-Sancho is the Chief of the Liver Vascular Biology Research Group at the IDIBAPS Research Institute - Hospital Clínic de Barcelona, Associate Researcher at the Department of Visceral Surgery and Medicine - University of Bern, & Scientific Director of the Spanish Research Consortium on Liver & Digestive Diseases (CIBEREHD). He graduated in Biochemistry receiving undergraduate research training in basic hemochromatosis at the London Metropolitan University, pursued pre-doctoral studies in basic portal hypertension at the University of Barcelona Medical School, and post-doctoral training at the Center for Excellence in Vascular Biology - Harvard Medical School & Brigham and Women's Hospital. In 2012 he obtained the "Ramón y Cajal Spanish tenure-track position and then promoted to his current senior position. Jordi's research focuses on liver vascular pathobiology with special interest in the role of sinusoidal cells, and their interactions, in acute and chronic liver diseases, and in aging. He (co-)authored more than 125 peer-reviewed original papers and reviews, and currently serves as Associate Editor for the Journal of Hepatology. In addition, he is invited professor in different universities within Spain and Europe and co-leads diverse educational initiatives including the LiverSeminars Program (liverseminars.eu), the 2018 EASL-Basic School of Hepatology, the 2020 APASL-Symposium on Regression of Portal Hypertension, the 2020 AASLD-Symposium on Senescence and Liver Diseases, the 2021 EASL-Symposium on Sinusoidal Cells in Liver Diseases and the 2023 AMH-Irwin Arias Symposium. Prof Gracia has been invited speaker in different national and international conferences, including the annual meetings of the European, American and Asia-Pacific associations of Hepatology. He has been member of the Scientific Committee of the Spanish Association for the Study of the Liver (AEEH) and the Steering Committee of the Portal Hypertension Special Interest Group of the American Association for the Study of Liver Diseases (AASLD). He is now member of the Governing Board of AEEH, the Basic Research Committee of AASLD and the Baveno Cooperation Steering Committee. In 2016 he received the Emerging Leader Award from the European Association for the Study of the Liver (EASL). He served as Scientific Secretary of the International Society for Hepatic Sinusoidal Research (ISHSR) from 2017-2022, being now the President-Elect of this Society.Professor Salvadó is currently a Professor in the Department of Biochemistry and Biotechnology, Rovira i Virgili University (Tarragona, Spain). She directs studies regarding Food Bioactive Ingredients and Oxidative Metabolism. Professor Salvadó graduated in 1978 from the University of Barcelona with a Degree in Chemistry Sciences. She gained her PhD in 1988, in the field of Amino acid Metabolism and Development, from the University of Barcelona. She performed post-doctorate studies at Centre de Recherches sur la Nutrition from the CNRS (Meudon-Bellevue, France) in 1989 and in Academisch Medisch Centrum from the Amsterdam University (The Netherlands) in 1992. She has performed a stage in the Centre of Technology of Food and Health (Reus, Spain) between 2013 and 2014. Between 1988 until 1994 she was associated professor at the University of Barcelona and at the Rovira i Virgili University. Since1994 she is Full Professor on Biochemistry and Molecular Biology. She is member of the Spanish Biochemistry and Molecular Society. Professor Salvadó has published over 80 peer-reviewed manuscripts based on original research and over 7 reviews.

Inhaltsangabe

Section 11. The Gastrointestinal system: anatomy and sources of oxidative
stress2. Redox mechanisms of reactive oxygen species in gastrointestinal
tract diseases3. Cancer in the gastrointestinal tract and oxidative
stress4. Crohn's disease and oxidative stress5. Mucosal injury and
oxidative stress6. Helicobacter pylori and reactive oxygen species7.
Inflammatory Bowel Diseases: The Crosslink Between Risk Factors and
Antioxidant Therapy8. Gut microbiota and oxidative stress9. Liver diseases
and oxidative stress10. Ischemia/reperfusion injury and oxidative stress11.
Necrotizing enterocolitis and oxidative stress12. Pancreatitis, pancreatic
cancer and oxidative stress13. Gallbladder disease - relevance of oxidative
stress
Section 214. Molecular mechanism underlying the actions of antioxidant
molecules15. Antioxidant vitamins, gastrointestinal protection and
oxidative stress16. Role of oxidative stress in portal hypertension in
cirrhosis17. Selenium, gastrointestinal protection and oxidative stress18.
Berries: gastrointestinal protection against oxidative stress and
inflammation19. Herbs, gastrointestinal protection and oxidative stress20.
Garlic extract, gastrointestinal protection, oxidative stress, and
inflammation21. Ginger extract (zingerone), gastrointestinal protection and
oxidative stress22. Ginseng and gastrointestinal protection23. Kiwi fruit
peptide kissper, gastrointestinal protection and oxidative stress24.
Magnesium, gastrointestinal protection and oxidative stress25. Melatonin,
gastrointestinal protection and oxidative stress26. Flavonoids for the
treatment of gastrointestinal inflammation in obesity, role of oxidative
stress27. Soy, gastrointestinal protection and oxidative stress 28.
Lycopenes as antioxidants in gastrointestinal diseases