The principles described in this book are fundamental to transforming healthcare operations. Matching unpredictable demand and supply in any asset-intensive industry requires sophisticated predictive and prescriptive algorithms deployed at scale. Others-Fedex, UPS, Airlines, Waze, Amazon-are doing it, and so can we in healthcare! Dr. Patrick Byrne, MBA Chairman, Cleveland Clinic Head and Neck Institute Healthcare leaders interested in digital transformation will benefit from reading this book. We all have to start using the sophisticated predictive and prescriptive models described in it to optimize access and contain costs. Steve Hess Chief Information Officer, UCHealth, Denver, Colorado The concepts shared in this book show how innovative methods can transform healthcare operations in a way that allows the organization to evolve on a comfortable path while experiencing dramatic advancements. Rebecca Kaul Chief Innovation Officer, MD Anderson Cancer Center Digital transformation is the next frontier for medicine and healthcare delivery. How does "math" fit in? How does AI provide the foundation for operational excellence and change? This highly readable book from two unique experts is a must read for healthcare leaders. Dr. Gary E. Bisbee, Jr., Ph.D., MBA Co-Founder and Chairman Emeritus, The Health Management Academy