Ravi Maddaly, Madhumitha Haridoss, Sai Keerthana Wuppalapati

Aggregates of cell lines on agarose hydrogels

Aggregates of cancer cell lines on agarose hydrogel matrix

• Broschiertes Buch

Produktbeschreibung

Established cancer cell lines have and continue to contribute tremendously for many discoveries and are some of the important tools for studies involving drug and biomarker discovery. Cell culture techniques has seen a multifold change with advancements in the technology; the biocompatible material available as culture supports and with enhancing understanding of cell physiology and culture behaviors. Culturing cells as monolayers in the 2D system are extremely important for various applications, likewise, the 3D systems of cell cultures have thrown valuable insights which were not possible with the 2D systems. Culturing cells in a 3D model is considered to bring in a closer in vivo effect to the cells and cells in such a system sure show marked changes compared to their 3D counterparts. Several matrices and supports are available for culturing cells in 3D. Agarose hydrogels offer us a useful combination of economy and ease of applications. We present here the uses of agarose hydrogels to obtain 3D aggregates of 3 different human cancer cell lines as three chapters and one chapter dedicated to the model applications of such a system.

Produktdetails

• Verlag: LAP Lambert Academic Publishing
• Aufl.
• Seitenzahl: 80
• Erscheinungstermin: 17. Januar 2012
• Englisch
• Abmessung: 220mm x 150mm x 5mm
• Gewicht: 137g
• ISBN-13: 9783847307556
• ISBN-10: 384730755X
• Artikelnr.: 34789263

Autorenporträt

Dr. M Ravi obtained doctorate in Human Genetics from Sri Ramachandra University, Chennai, India. He is presently an Associate Professor in Department of Human Genetics of the same University. He authored several research papers and 3 books, Member of National Academy of Sciences, India & Editor of the journal ¿Advanced Biotech¿.