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Bioflavonoids are a large class of antioxidants and belong to secondary metabolites. These are distributed in all plant species. Almost all vegetables, fruits and herbs contain a certain amount of bioflavonoids. These are acts as cell cycle inhibitors and chemical messengers. It shows various pharmacological activities like anti-oxidant activity, anti-cancer activity, wound healing activity, anti-inflammatory activity, Immunomodulatory effect, anti-inflammatory activity, anti-arthritic activity and anti-diabetic activities etc. Mainly Quercetin, Rutin and Kaempferol flavonoids are played as good medicinal properties. Bioflavonoids have also been shown to interact with certain drugs and nutrients.